| 919006497 | XP_013387286 | PDGF-B | vascular endothelial growth factor D [Lingula anatina] | None | blastp | alignment |
| XP_013387286.1 | XP_013387286 | PDGF-D | vascular endothelial growth factor D [Lingula anatina] | None | blastp | alignment |
T-COFFEE, Version_11.00.8cbe486 (2014-08-12 22:05:29 - Revision 8cbe486 - Build 477)
Cedric Notredame
CPU TIME:0 sec.
SCORE=815
*
BAD AVG GOOD
*
XP_013387286.1 : 71
XP_013387286.1_ : 70
VEGF-C : 82
VEGF-D : 81
VEGF-A206 : 84
VEGF-A165 : 87
VEGF-A121 : 87
VEGF-B186 : 81
VEGF-B167 : 81
PlGF-1 : 82
VEGF-F : 85
PDGF-A : 80
PDGF-B : 75
PDGF-C : 82
PDGF-D : 74
cons : 81
XP_013387286.1 ---------------------------------
XP_013387286.1_ ---------------------------------
VEGF-C ---------------------------------
VEGF-D ---------------------------------
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C --MSLFGLLLLTSALAGQRQGTQAESNLSSKFQ
PDGF-D MHRLIFVYTLICANFCSCRDTSATPQSASIKAL
cons
XP_013387286.1 ---------------------------------
XP_013387286.1_ ---------------------------------
VEGF-C ---------------------------------
VEGF-D ---------------------------------
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C FSSN---KEQNGVQDP-QHERIITVSTNGSIHS
PDGF-D RNANLRRDESNHLTDLYRRDETIQVKGNGYVQS
cons
XP_013387286.1 ---------------------------------
XP_013387286.1_ ---------------------------------
VEGF-C ---------------------------------
VEGF-D ---------------------------------
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDER
PDGF-D PRFPNSYPRNLLLTWRLHS-QENTRIQLVFDNQ
cons
XP_013387286.1 ---------------------------------
XP_013387286.1_ ---------------------------------
VEGF-C ---------------------------------
VEGF-D ---------------------------------
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C FGLEDPEDDICKYDFVEVEEPSDGTIL--GRWC
PDGF-D FGLEEAENDICRYDFVEVEDISETSTIIRGRWC
cons
XP_013387286.1 ---------------------------------
XP_013387286.1_ ---------------------------------
VEGF-C --------------------MHLLGFFSVACSL
VEGF-D --------------------MYREWVVVNVFMM
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C GSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFC
PDGF-D GHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFK
cons
XP_013387286.1 ------MSWV-AYF------------VCVFAVL
XP_013387286.1_ ------MSWV-AYF------------VCVFAVL
VEGF-C LAAAL-LPGPREAPAAAAAFESG---LDLSDAE
VEGF-D LYVQL-VQGS-------------------SNEH
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ------MRTLACLL------------LLGCGYL
PDGF-B ------MNRCWALF------------LSLCCYL
PDGF-C IHYNIVMPQFTEAV-------------------
PDGF-D IYYSL-LEDFQPAAASETNWESVTSSISGVSYN
cons
XP_013387286.1 HGSLADPPASF-LLKADRFRDPD----DFIREF
XP_013387286.1_ HGSLADPPASF-LLKADRFRDPD----DFIREF
VEGF-C PDAGEATAYAS-KDLEEQLR--SVSSVDELMTV
VEGF-D GPVKRSSQSTL-ERSEQQIR--AASSLEELLRI
VEGF-A206 -----------------------MNFLLSWVHW
VEGF-A165 -----------------------MNFLLSWVHW
VEGF-A121 -----------------------MNFLLSWVHW
VEGF-B186 ---------------------------MSPLLR
VEGF-B167 ---------------------------MSPLLR
PlGF-1 ---------------------------MPVMRL
VEGF-F -----------------------------MAAY
PDGF-A AHVLAEEAEIP-REVIERLARSQIHSIRDLQRL
PDGF-B RLVSAEGDPIP-EELYEMLSDHSIRSFDDLQRL
PDGF-C SPSVLPPSALPLDLLNNAIT--AFSTLEDLIRY
PDGF-D SPSVTDPTLIA-DALDKKIA--EFDTVEDLLKY
cons
XP_013387286.1 VD-------------TGS------ISSQQM---
XP_013387286.1_ VD-------------TGS------ISSQQM---
VEGF-C LYPEY-------WKMYKCQLRKGG----WQHNR
VEGF-D THSED-------WKLWRCRLRLKS----FT---
VEGF-A206 SLALLLYLHH-------AKWSQAA----PM---
VEGF-A165 SLALLLYLHH-------AKWSQAA----PM---
VEGF-A121 SLALLLYLHH-------AKWSQAA----PM---
VEGF-B186 RLLLAALLQLAP-----AQAPVSQ----PD---
VEGF-B167 RLLLAALLQLAP-----AQAPVSQ----PD---
PlGF-1 FPCFLQLLAGLALPAVPPQWALSA----GN---
VEGF-F LLAVAILFCI-------QGWPSGT----VQ---
PDGF-A LEIDSV------GSEDSLDTSLRAHGVHAT---
PDGF-B LHGDP-------GEEDGAELDLNMTRSHSG---
PDGF-C LEPER-------WQLDLEDLYRPT----WQ---
PDGF-D FNPES-------WQEDLENMYLDT----PR---
cons
XP_013387286.1 -EEINSA---IRDMREQGRRPNRYTV-------
XP_013387286.1_ -EEINSA---IRDMREQGRRPNRYTV-------
VEGF-C EQANLNS---RTE-------------ET-----
VEGF-D -SMDSRS---ASH-------------RS-----
VEGF-A206 -AEGGGQ---NHH-------------EV-----
VEGF-A165 -AEGGGQ---NHH-------------EV-----
VEGF-A121 -AEGGGQ---NHH-------------EV-----
VEGF-B186 -APGHQR-------------------KV-----
VEGF-B167 -APGHQR-------------------KV-----
PlGF-1 -GSSEV--------------------EV-----
VEGF-F -G------------------------QV-----
PDGF-A -KHVPEK---R-------------PLPIRRKRS
PDGF-B -GELESL---A-----------------RGRRS
PDGF-C -LLGKAFVFGRKS-------------RV-----
PDGF-D -YRGRSY-HDRKS-------------K------
cons
XP_013387286.1 A-----S-------------TNTLNDGCIPEQT
XP_013387286.1_ A-----S-------------TNTLNDGCIPEQT
VEGF-C I---KFAAAHYNTEILKSIDNEWRKTQCMPREV
VEGF-D T---RFAATFYDIETLKVIDEEWQRTQCSPRET
VEGF-A206 V---KFM-------------DVYQRSYCHPIET
VEGF-A165 V---KFM-------------DVYQRSYCHPIET
VEGF-A121 V---KFM-------------DVYQRSYCHPIET
VEGF-B186 V---SWI-------------DVYTRATCQPREV
VEGF-B167 V---SWI-------------DVYTRATCQPREV
PlGF-1 V---PFQ-------------EVWGRSYCRALER
VEGF-F R---PFL-------------EVHERSACQARET
PDGF-A I-------------------EEAVPAVCKTRTV
PDGF-B LGSLTIA-------------EPAMIAECKTRTE
PDGF-C VDLNLLT-------------EEVRLYSCTPRNF
PDGF-D VDLDRLN-------------DDAKRYSCTPRNY
cons * .
XP_013387286.1 AVALNE----GS-DPNVLTFPVCVKVSRCGGCC
XP_013387286.1_ AVALNE----GS-DPNVLTFPVCVKVSRCGGCC
VEGF-C CIDVGKEF--GV-ATNTFFKPPCVSVYRCGGCC
VEGF-D CVEVASEL--GK-STNTFFKPPCVNVFRCGGCC
VEGF-A206 LVDIFQEY--PD-EIEYIFKPSCVPLMRCGGCC
VEGF-A165 LVDIFQEY--PD-EIEYIFKPSCVPLMRCGGCC
VEGF-A121 LVDIFQEY--PD-EIEYIFKPSCVPLMRCGGCC
VEGF-B186 VVPLTVEL--MGTVAKQLV-PSCVTVQRCGGCC
VEGF-B167 VVPLTVEL--MGTVAKQLV-PSCVTVQRCGGCC
PlGF-1 LVDVVSEY--PS-EVEHMFSPSCVSLLRCTGCC
VEGF-F LVPILQEY--PD-EISDIFRPSCVAVLRCSGCC
PDGF-A IYEIPRSQVDPT-SANFLIWPPCVEVKRCTGCC
PDGF-B VFEISRRLIDRT-NANFLVWPPCVEVQRCSGCC
PDGF-C SVSIREEL---K-RTDTIFWPGCLLVKRCGGNC
PDGF-D SVNIREEL---K-LANVVFFPRCLLVQRCGGNC
cons : . . * *: : ** * *
XP_013387286.1 GSETTTCGPSPGGT---VTVSK-----RVMKFE
XP_013387286.1_ GSETTTCGPSPGGT---VTVSK-----RVMKFE
VEGF-C NSEGLQCMNTST-----SYLSK-----TLFEIT
VEGF-D NEESLICMNTST-----SYISK-----QLFEIS
VEGF-A206 NDEGLECVPTEE-----SNITM-----QIMRIK
VEGF-A165 NDEGLECVPTEE-----SNITM-----QIMRIK
VEGF-A121 NDEGLECVPTEE-----SNITM-----QIMRIK
VEGF-B186 PDDGLECVPTGQ-----HQVRM-----QILMIR
VEGF-B167 PDDGLECVPTGQ-----HQVRM-----QILMIR
PlGF-1 GDENLHCVPVET-----ANVTM-----QLLKIR
VEGF-F TDESLKCTPVGK-----HTVDL-----QIMRVN
PDGF-A NTSSVKCQPSRVHHRSVKVAKV-----EYVRKK
PDGF-B NNRNVQCRPTQVQLRPVQVRKI-----EIVRKK
PDGF-C ACCLHNCNECQC-----VPSKVTKKYHEVLQLR
PDGF-D GCGTVNWRSCTC-----NSGKTVKKYHEVLQFE
cons .
XP_013387286.1 ---------GTAYNLNNLKYIG---AETKLIEE
XP_013387286.1_ ---------GTAYNLNNLKYIG---AETKLIEE
VEGF-C V---PL---SQ------G--PK---PVTISFAN
VEGF-D V---PL---TS------V--PE---LVPVKVAN
VEGF-A206 P--------HQ------G--QH---IGEMSFLQ
VEGF-A165 P--------HQ------G--QH---IGEMSFLQ
VEGF-A121 P--------HQ------G--QH---IGEMSFLQ
VEGF-B186 ---------YP------S--SQ---LGEMSLEE
VEGF-B167 ---------YP------S--SQ---LGEMSLEE
PlGF-1 S--------GD------R--PS---YVELTFSQ
VEGF-F P-------RTQ------S--SK---MEVMKFTE
PDGF-A ------------------PKLK---EVQVRLEE
PDGF-B ------------------PIFK---KATVTLED
PDGF-C P---KTGVRGL------H--KSLTD---VALEH
PDGF-D PGHIKRRGR-----------AKTMALVDIQLDH
cons . .
XP_013387286.1 HTACQCQCKVK-------A--GDCNPAVHIY--
XP_013387286.1_ HTACQCQCKVK-------A--GDCNPAVHIY--
VEGF-C HTSCRCMSKLDVYRQV--H--SII---------
VEGF-D HTGCKCLP--TAPRHP--Y--SII---------
VEGF-A206 HNKCECRPKKD--RARQEK--KSVRGKGKGQKR
VEGF-A165 HNKCECRPKKD--RA------------------
VEGF-A121 HNKCECRPKKD--RA------------------
VEGF-B186 HSQCECRPKKK--DS-------A----------
VEGF-B167 HSQCECRPKKK--DS-------A----------
PlGF-1 HVRCECRPLRE--KM------------------
VEGF-F HTACECRPR------------------------
PDGF-A HLECACATTSL--NPD--YREEDTGRPR-----
PDGF-B HLACKCETVAA-------AR--PVTRSPGGS--
PDGF-C HEECDCVCRGS--TGG-----------------
PDGF-D HERCDCICSSR--PPR-----------------
cons * * *
XP_013387286.1 ------------------------------DQD
XP_013387286.1_ ------------------------------DQD
VEGF-C --------RRSLPA-------------------
VEGF-D --------RRSI---------------------
VEGF-A206 KRKKSRYKSWSVYVGARCCLMPWSLPGPHP-CG
VEGF-A165 RQE-------------------------NP-CG
VEGF-A121 RQEK-----------------------------
VEGF-B186 -VK---------------------PD-------
VEGF-B167 -VK---------------------PDSPRPLCP
PlGF-1 KPE-----------------------RRRP-KG
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ------------------------------QEQ
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 ------------------N-------C--RCKC
XP_013387286.1_ ------------------N-------C--RCKC
VEGF-C --------------TLPQ--------C--QAAN
VEGF-D --------------QIPEE----DR-C--SHSK
VEGF-A206 PCSE--RR-KHLFVQDPQT-------C--KCSC
VEGF-A165 PCSE--RR-KHLFVQDPQT-------C--KCSC
VEGF-A121 ---------------------------------
VEGF-B186 RAATPH---HR---PQPRSVPGWDSAPGAPSPA
VEGF-B167 RCTQHH---QR---P-------DPRTCRCRCR-
PlGF-1 RGKR--RR-EK---QRPTD-------C------
VEGF-F -RKQGEPDGPK---EKPRR-GG----V--RAKF
PDGF-A E---------S---GKKRK-------R--KRLK
PDGF-B R---------A---KTPQT-------R--VTIR
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 KVPQ-ISCS-SGMVWDDSTCRCISKDT------
XP_013387286.1_ KVPQ-ISCS-SGMVWDDSTCRCISKDT------
VEGF-C KTCP------TNYMWNNHICRCLAQED------
VEGF-D KLCP------IDMLWDSNKCKCVLQEE------
VEGF-A206 KNTD-SRCKARQLELNERTCRCDKPRR------
VEGF-A165 KNTD-SRCKARQLELNERTCRCDKPRR------
VEGF-A121 ---------------------CDKPRR------
VEGF-B186 DITHPTPAPGPSAHAAPSTTSALTPGPAAAAAD
VEGF-B167 -RRSFLRCQGRGLELNPDTCRCRKLRR------
PlGF-1 -----------------HLCGDAVPRR------
VEGF-F PFV------------------------------
PDGF-A PT-------------------------------
PDGF-B TVRVRRPPKGKHRKFKHTHDKTALKET------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 --VALLTWRARTTGEAAPSFSA-----------
XP_013387286.1_ --VALLTWRARTTGEAAPSFSA-----------
VEGF-C --FM---FSSDAGDDSTDGFHDICGPNKELDEE
VEGF-D --N------PLAGTEDHSHLQE-----------
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 AAAS------SVA--------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B --LGA----------------------------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 ---------------QPQQA-------------
XP_013387286.1_ ---------------QPQQA-------------
VEGF-C TCQCVCRAGLRPASCGPHKELDRNSCQCVCKNK
VEGF-D -----------PALCGPHMM-------------
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 --------ERVVASDPCDG---CTCGRRWNPTP
XP_013387286.1_ --------ERVVASDPCDG---CTCGRRWNPTP
VEGF-C LFPSQCGANREFDENTCQCVCKRTCPRNQPLNP
VEGF-D -----------FDEDRCECVCKTPCPKDLIQHP
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 GA---------------------GNTCECVHSS
XP_013387286.1_ GA---------------------GNTCECVHSS
VEGF-C GKCAC-ECTESPQKCLLKGKKFHHQTCSC----
VEGF-D KNCSCFECKESLETCCQKHKLFHPDTCSCEDRC
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 GRSRRPCPARG----------------------
XP_013387286.1_ GRSRRPCPARG----------------------
VEGF-C --YRRPCTNRQKACEPGFSYSEEVCRCVPSYWK
VEGF-D PFHTRPCASGKTACAKHCRFPKEKRAAQGPHSR
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------------------------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons
XP_013387286.1 -----
XP_013387286.1_ -----
VEGF-C RPQMS
VEGF-D KNP--
VEGF-A206 -----
VEGF-A165 -----
VEGF-A121 -----
VEGF-B186 -KGGA
VEGF-B167 -----
PlGF-1 -----
VEGF-F -----
PDGF-A -----
PDGF-B -----
PDGF-C -----
PDGF-D -----
cons