Individual alignments and phylogenetic tree for taxon cephalochordata

cephalochordata

XP_019621834

PDGF-B

PREDICTED: vascular endothelial growth factor C-like [Branchiostoma belcheri]

None



           1                                               50
XP_019621834.1  ~~~~~~~~~~~MACFYGKLNQVQLGDSAMSVYSLFVLVSLLGKPFGYSHF
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019621834.1  DTRSRLDRYLAGVGSTEDLLRLYYPEDWRKIMCHMRGGGERYQSDYQSDY
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019621834.1  SEDGSGMGRSAAAATMDLMDIVNKVDEEWEKAFCKPRETAVDAATELQAP
VEGF-C          SRTEETIK...FAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXX

           151                                            200
XP_019621834.1  TDVTYRPSCVSVFRCGGCCNDERYECIASEKNMVSKTIFEVGL...RGPY
VEGF-C          TNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPK
VEGFC_signature XXXXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_019621834.1  PVTRPFENHTRCECRAKLGARTSFLYQRMNYKRAVSPHINTRCYAPNKTC
VEGF-C          PVTISFANHTSCRCMSKLDVYR....QVHSIIRRSLPATLPQCQAANKTC
VEGFC_signature XXXXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019621834.1  GPYEKWDDRDCACVRAVTIIDDDDHCGPLKEWREDECACVCKRPCPQRFI
VEGF-C          PTNYMWNNHICRCLAQEDFMFSSDAG........DDSTDGFHDICGPNKE
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019621834.1  EDLQTCECRCPPYYQTRCQKKGQKLHWGTCKCVPKDCHYVMACPAGTVYS
VEGF-C          LDEETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFD
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019621834.1  TDVCACVMLAGG~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ENTCQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401                            434
XP_019621834.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

260833542

XP_002611716

PDGF-B

hypothetical protein BRAFLDRAFT_63593 [Branchiostoma floridae]

None

blastp

alignment



           1                                               50
XP_002611716.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_002611716.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_002611716.1  ~~~~MALGWRACQQGGGINTEVDEEWEKAFCKPRETAVDAATELQAPTDV
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_002611716.1  TYRPSCVSVFRCGGCCNDEMYECIASEKNMVSKTIFEVGL...RGPNPVT
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_002611716.1  KPFENHTRCECRAKMGASSSFLFQRGNYKRAVSPHVNTRCYAPNKTCGPH
VEGF-C          ISFANHTSCRCMSKLDVYR....QVHSIIRRSLPATLPQCQAANKTCPTN
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_002611716.1  QKWDDRDCACVSDLTVIADDDHCGPLKEWREDECACVCKRPCPRRFIEDP
VEGF-C          YMWNNHICRCLAQEDFMFSSDAG........DDSTDGFHDICGPNKELDE
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_002611716.1  QTCECTCPPYYRNRCQRIGHRLHWGTCKCVPKICHYVVACPMGTVYSEDV
VEGF-C          ETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_002611716.1  CACVMLAGG~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPC
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401                         431
XP_002611716.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          TNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

1126225966

XP_019647399

PDGF-B

PREDICTED: vascular endothelial growth factor C-like isoform X1 [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  ~MFSRHPSAKTAFSETILCWAGRAKIPFQVLNKLLDVKNPADLFHLFNVS
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA

           51                                             100
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  TDSIGPEMSGPSTDFIPDSVLRDDSFPTIAAKDKPIRGRLGGLGGDQGIV
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN

           101                                            150
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXX..
XP_019647399.1  LLDDSALGRNPFLSEKVTVSRQGADVVTSLLSEIDFCSPRGMEVKVPNER
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVAT..

           151                                            200
VEGFC_signature .XXXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXX
XP_019647399.1  PSTIVVPSCVNLQRCGGCCHADIFQCEPLEIKNTTITVMKLGLAEGGDLV
VEGF-C          .NTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPK

           201                                            250
VEGFC_signature XXXXX...XXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  LEAIEGIEMEEHASCQCGCKVKPHHCNPTIHKYEDCACS..CLSPRRDCE
VEGF-C          PVTIS...FANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCP

           251                                            300
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  EGKVWDEKECQCVCRSGETNCRKRYYWSPDRCECLCADRPCPTGRTLDFN
VEGF-C          TNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCV

           301                                            350
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  TCKCKRNTSRRLQDSRTPCKRRCPPGALLNRRHCTCSQGQGRGRMLSPFL
VEGF-C          CRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCK

           351                                            400
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  PFDYGSGDN~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKA

                401                   425
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  ~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CEPGFSYSEEVCRCVPSYWKRPQMS

1126225972

XP_019647402

PDGF-B

PREDICTED: vascular endothelial growth factor C-like isoform X3 [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019647402.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019647402.1  ~MSGPSTDFIPDSVLRDDSFPTIAAKDKPIRGRLGGLGGDQGIVLLDDSA
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019647402.1  LGRNPFLSEKVTVSRQGADVVTSLLSEIDFCSPRGMEVKVPNER...PST
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_019647402.1  IVVPSCVNLQRCGGCCHADIFQCEPLEIKNTTITVMKLGLAEGGDLVLEA
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQ...GPK
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXX...XXX

           201                                            250
XP_019647402.1  IEGIEMEEHASCQCGCKVKPHHCNPTIHKYEDCACS..CLSPRRDCEEGK
VEGF-C          PVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNY
VEGFC_signature XXXXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019647402.1  VWDEKECQCVCRSGETN...............CRKRYYWSPDRCECLCAD
VEGF-C          MWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019647402.1  ....RPCPTGRTLDFNTCKCKRN........TSRRLQDS...RTPCKRRC
VEGF-C          GLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTC
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019647402.1  PPGALLNRRHCTCSQGQGRGRMLSPFLPFDYGSGDN~~~~~~~~~~~~~~
VEGF-C          PRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEP
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401                422
XP_019647402.1  ~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          GFSYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~

1126225968

XP_019647400

PDGF-B

PREDICTED: vascular endothelial growth factor C-like isoform X2 [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019647400.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019647400.1  ~~~MALQSELRLILLLLTCTAIQGEIPFQVLNKLLDVKNPADLFHLFNVS
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019647400.1  TDSIGPEMSGPSTDFIPDSVLRDDSFPTIAAKDKPIRGRLGGLGGDQGIV
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_019647400.1  LLDDSALGRNPFLSEKVTVSRQGADVVTSLLSEIDFCSPRGMEVKVPNER
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_019647400.1  PSTIVVPSCVNLQRCGG..CCHADIFQCEPLEIKNTTITVMKLGLAEGGD
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019647400.1  LVLEAIEGIEMEEHASCQCGCKVKPHH..CNP.TIHKYEDCACSCLSPRR
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019647400.1  ..DCEEGKVWDEKECQCVCR..SGETNCRKRYYWSPDRCECLCADRPCPT
VEGF-C          PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCK.RTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019647400.1  GRTLDFNTCKCKRNTSRR..LQDSRTPCKRRCPPG.ALLNRRHCTCSQGQ
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_019647400.1  GRGRMLSPFLPFDYGSGDN~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

1126185416

XP_019625376

PDGF-B

PREDICTED: vascular endothelial growth factor A-like [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019625376.1  ~~~~~~MSMYISLGLSSLLVVLGATQRASSHEDRPVVPEIPLHIRQLLRN
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019625376.1  VTSYEELKTTFNLDIFSAADDRFSLTGPPPCIPREVPVPVP..VDAEPNV
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_019625376.1  VLWPSCVSVARCGGCCNSDLYECQATRSSSQVSSILKLFYAPGNPNSQPF
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNT.STSYLSKTLFEITVPLSQGPKPV
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXX.XXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_019625376.1  NTAFDQVHVERHDECACVCKNKRLCDLRTHFFDDNTCECVCRVRGGCSVS
VEGF-C          TISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMW
VEGFC_signature XXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019625376.1  AVSDNLCNRQCSAGFRLDE..DSCRCRVDGGALFGGLGRRRRRTEP~~~~
VEGF-C          NNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGL
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

260785480

XP_002587789

PDGF-B

hypothetical protein BRAFLDRAFT_92234 [Branchiostoma floridae], PDGF signature programmatically detected

None

blastp

alignment



           1                                               50
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MHL
XP_002587789.1  MSIFTSFVLLSSLVALGATQRAPSPEESLLTSEIPVEIQRLLRNVTSYEE

           51                                             100
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          LGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATAYAS
XP_002587789.1  LKATFNLDIFTAEDDRFSLTGPPPCIPREMPVPVPLDAEPNVVLWPSCVS

           101                                            150
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          KDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRT
XP_002587789.1  VARCGGCCNSDLYECQASRSSSQVFSVLKLFYSPGNPSSQPFNNAFDQVQ

           151                                            200
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXXXXX
VEGF-C          EETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFK
XP_002587789.1  VERHDQCACVCKNKHLCDLRTHFFDDNTCDCVCRHRGGCVLGAVSDDSCS

           201                                            250
VEGFC_signature PXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VEGF-C          PPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVTISF
XP_002587789.1  RQCPSGWKLDEDACQCRLDGRALFGSLGRRCVLGAVSDDSCSRQCPSGWK

           251                                            300
VEGFC_signature XXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWNNHI
XP_002587789.1  LDEDACQCRLDGRALFGSLGRRIQGSRAPGGQCEFEFHLVGNFVKTSNMS

           301                                            350
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLRPAS
XP_002587789.1  SSSSSPSSPEEQVDDEYQP.PGAAPFKLKSPPRGKGIEPKEDKDYEAKVG

           351                                            400
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPL
XP_002587789.1  LGKTLQTISLLGYMKHYRSIPGPHLVIVPKSTLANWMNEFEHWCPSIRTV

           401                                            450
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFSYSE
XP_002587789.1  SLIGDQEKRAAIIRDQIMPGEWDVCITSYEMALREKAVFKKFNWRYLVID

           451                                            500
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          EVCRCVPSYWKRPQMS~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  EAHRIKNEKSKLSEIVRTFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDV

           501                                            550
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  FNSSEDFDAWFDTNACLDKDDMVARLHTLSEIVRTFKTTNRLLLTGTPLQ

           551                                            600
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  NNLHELWSLLNFLLPDVFNSSEDFDAWFDTNACLDKDDMVARLHTYQPPG

                601                     627
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  AAPFKLKSPPRGKGIEPKEDKDYEAKV

260833544

XP_002611717

VEGF-C

hypothetical protein BRAFLDRAFT_63592 [Branchiostoma floridae]

VEGF-C

blastp

alignment



           1                                               50
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
XP_002611717.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~MSVYSLFVLVSLLGKPFGYSHF

           51                                             100
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
XP_002611717.1  DTRSRLDRHLAGVGSTEDLIRLYYPQQWRKIMCHMRGGGERYLSDYQSDY

           101                                            150
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
XP_002611717.1  SEDGSGMGRSAAAATMDLMDIVN....KDSSEPYFEVVGFWTTHRSLIDV

           151                                            200
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
XP_002611717.1  WVCAGHREVSEQPSCEAFARQLWGLFSFDEVGGMAQTGNGRQNRIKVKTR

           201                                            250
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
XP_002611717.1  LHSVWARRPVRPLSRALLPEDGL~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
XP_002611717.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRN
XP_002611717.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          QPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFS
XP_002611717.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401             419
VEGFC_signature ~~~~~~~~~~~~~~~~~~~
VEGF-C          YSEEVCRCVPSYWKRPQMS
XP_002611717.1  ~~~~~~~~~~~~~~~~~~~

XP_002587789.1

XP_002587789

PDGF-D

hypothetical protein BRAFLDRAFT_92234, partial [Branchiostoma floridae], PDGF signature programmatically detected

None

blastp

alignment



           1                                               50
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MHL
XP_002587789.1  MSIFTSFVLLSSLVALGATQRAPSPEESLLTSEIPVEIQRLLRNVTSYEE

           51                                             100
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          LGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATAYAS
XP_002587789.1  LKATFNLDIFTAEDDRFSLTGPPPCIPREMPVPVPLDAEPNVVLWPSCVS

           101                                            150
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          KDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRT
XP_002587789.1  VARCGGCCNSDLYECQASRSSSQVFSVLKLFYSPGNPSSQPFNNAFDQVQ

           151                                            200
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXXXXX
VEGF-C          EETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFK
XP_002587789.1  VERHDQCACVCKNKHLCDLRTHFFDDNTCDCVCRHRGGCVLGAVSDDSCS

           201                                            250
VEGFC_signature PXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
VEGF-C          PPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVTISF
XP_002587789.1  RQCPSGWKLDEDACQCRLDGRALFGSLGRRCVLGAVSDDSCSRQCPSGWK

           251                                            300
VEGFC_signature XXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWNNHI
XP_002587789.1  LDEDACQCRLDGRALFGSLGRRIQGSRAPGGQCEFEFHLVGNFVKTSNMS

           301                                            350
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLRPAS
XP_002587789.1  SSSSSPSSPEEQVDDEYQP.PGAAPFKLKSPPRGKGIEPKEDKDYEAKVG

           351                                            400
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPL
XP_002587789.1  LGKTLQTISLLGYMKHYRSIPGPHLVIVPKSTLANWMNEFEHWCPSIRTV

           401                                            450
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGFSYSE
XP_002587789.1  SLIGDQEKRAAIIRDQIMPGEWDVCITSYEMALREKAVFKKFNWRYLVID

           451                                            500
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          EVCRCVPSYWKRPQMS~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  EAHRIKNEKSKLSEIVRTFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDV

           501                                            550
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  FNSSEDFDAWFDTNACLDKDDMVARLHTLSEIVRTFKTTNRLLLTGTPLQ

           551                                            600
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  NNLHELWSLLNFLLPDVFNSSEDFDAWFDTNACLDKDDMVARLHTYQPPG

                601                     627
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_002587789.1  AAPFKLKSPPRGKGIEPKEDKDYEAKV

XP_019621834.1

XP_019621834

PDGF-D

PREDICTED: vascular endothelial growth factor C-like [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019621834.1  ~~~~~~~~~~~MACFYGKLNQVQLGDSAMSVYSLFVLVSLLGKPFGYSHF
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019621834.1  DTRSRLDRYLAGVGSTEDLLRLYYPEDWRKIMCHMRGGGERYQSDYQSDY
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019621834.1  SEDGSGMGRSAAAATMDLMDIVNKVDEEWEKAFCKPRETAVDAATELQAP
VEGF-C          SRTEETIK...FAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXX

           151                                            200
XP_019621834.1  TDVTYRPSCVSVFRCGGCCNDERYECIASEKNMVSKTIFEVGL...RGPY
VEGF-C          TNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPK
VEGFC_signature XXXXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_019621834.1  PVTRPFENHTRCECRAKLGARTSFLYQRMNYKRAVSPHINTRCYAPNKTC
VEGF-C          PVTISFANHTSCRCMSKLDVYR....QVHSIIRRSLPATLPQCQAANKTC
VEGFC_signature XXXXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019621834.1  GPYEKWDDRDCACVRAVTIIDDDDHCGPLKEWREDECACVCKRPCPQRFI
VEGF-C          PTNYMWNNHICRCLAQEDFMFSSDAG........DDSTDGFHDICGPNKE
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019621834.1  EDLQTCECRCPPYYQTRCQKKGQKLHWGTCKCVPKDCHYVMACPAGTVYS
VEGF-C          LDEETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFD
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019621834.1  TDVCACVMLAGG~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          ENTCQCVCKRTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401                            434
XP_019621834.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RPCTNRQKACEPGFSYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

XP_019647400.1

XP_019647400

PDGF-D

PREDICTED: vascular endothelial growth factor C-like isoform X2 [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019647400.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019647400.1  ~~~MALQSELRLILLLLTCTAIQGEIPFQVLNKLLDVKNPADLFHLFNVS
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019647400.1  TDSIGPEMSGPSTDFIPDSVLRDDSFPTIAAKDKPIRGRLGGLGGDQGIV
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_019647400.1  LLDDSALGRNPFLSEKVTVSRQGADVVTSLLSEIDFCSPRGMEVKVPNER
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_019647400.1  PSTIVVPSCVNLQRCGG..CCHADIFQCEPLEIKNTTITVMKLGLAEGGD
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019647400.1  LVLEAIEGIEMEEHASCQCGCKVKPHH..CNP.TIHKYEDCACSCLSPRR
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019647400.1  ..DCEEGKVWDEKECQCVCR..SGETNCRKRYYWSPDRCECLCADRPCPT
VEGF-C          PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCK.RTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019647400.1  GRTLDFNTCKCKRNTSRR..LQDSRTPCKRRCPPG.ALLNRRHCTCSQGQ
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_019647400.1  GRGRMLSPFLPFDYGSGDN~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

XP_019647399.1

XP_019647399

PDGF-D

PREDICTED: vascular endothelial growth factor C-like isoform X1 [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  ~MFSRHPSAKTAFSETILCWAGRAKIPFQVLNKLLDVKNPADLFHLFNVS
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA

           51                                             100
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  TDSIGPEMSGPSTDFIPDSVLRDDSFPTIAAKDKPIRGRLGGLGGDQGIV
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN

           101                                            150
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXX..
XP_019647399.1  LLDDSALGRNPFLSEKVTVSRQGADVVTSLLSEIDFCSPRGMEVKVPNER
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVAT..

           151                                            200
VEGFC_signature .XXXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXX
XP_019647399.1  PSTIVVPSCVNLQRCGGCCHADIFQCEPLEIKNTTITVMKLGLAEGGDLV
VEGF-C          .NTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPK

           201                                            250
VEGFC_signature XXXXX...XXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  LEAIEGIEMEEHASCQCGCKVKPHHCNPTIHKYEDCACS..CLSPRRDCE
VEGF-C          PVTIS...FANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCP

           251                                            300
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  EGKVWDEKECQCVCRSGETNCRKRYYWSPDRCECLCADRPCPTGRTLDFN
VEGF-C          TNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCV

           301                                            350
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  TCKCKRNTSRRLQDSRTPCKRRCPPGALLNRRHCTCSQGQGRGRMLSPFL
VEGF-C          CRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCK

           351                                            400
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  PFDYGSGDN~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RTCPRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKA

                401                   425
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~
XP_019647399.1  ~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          CEPGFSYSEEVCRCVPSYWKRPQMS

XP_019647402.1

XP_019647402

PDGF-D

PREDICTED: vascular endothelial growth factor C-like isoform X3 [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019647402.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019647402.1  ~MSGPSTDFIPDSVLRDDSFPTIAAKDKPIRGRLGGLGGDQGIVLLDDSA
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019647402.1  LGRNPFLSEKVTVSRQGADVVTSLLSEIDFCSPRGMEVKVPNER...PST
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_019647402.1  IVVPSCVNLQRCGGCCHADIFQCEPLEIKNTTITVMKLGLAEGGDLVLEA
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQ...GPK
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXX...XXX

           201                                            250
XP_019647402.1  IEGIEMEEHASCQCGCKVKPHHCNPTIHKYEDCACS..CLSPRRDCEEGK
VEGF-C          PVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNY
VEGFC_signature XXXXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019647402.1  VWDEKECQCVCRSGETN...............CRKRYYWSPDRCECLCAD
VEGF-C          MWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019647402.1  ....RPCPTGRTLDFNTCKCKRN........TSRRLQDS...RTPCKRRC
VEGF-C          GLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTC
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019647402.1  PPGALLNRRHCTCSQGQGRGRMLSPFLPFDYGSGDN~~~~~~~~~~~~~~
VEGF-C          PRNQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEP
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401                422
XP_019647402.1  ~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          GFSYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~

XP_019625376.1

XP_019625376

PDGF-D

PREDICTED: vascular endothelial growth factor A-like [Branchiostoma belcheri]

None

blastp

alignment



           1                                               50
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_019625376.1  ~~~~~~MSMYISLGLSSLLVVLGATQRASSHEDRPVVPEIPLHIRQLLRN
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_019625376.1  VTSYEELKTTFNLDIFSAADDRFSLTGPPPCIPREVPVPVP..VDAEPNV
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_019625376.1  VLWPSCVSVARCGGCCNSDLYECQATRSSSQVSSILKLFYAPGNPNSQPF
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNT.STSYLSKTLFEITVPLSQGPKPV
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXX.XXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_019625376.1  NTAFDQVHVERHDECACVCKNKRLCDLRTHFFDDNTCECVCRVRGGCSVS
VEGF-C          TISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMW
VEGFC_signature XXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_019625376.1  AVSDNLCNRQCSAGFRLDE..DSCRCRVDGGALFGGLGRRRRRTEP~~~~
VEGF-C          NNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGL
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_019625376.1  ~~~~~~~~~~~~~~~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

T-COFFEE, Version_11.00.8cbe486 (2014-08-12 22:05:29 - Revision 8cbe486 - Build 477)
Cedric Notredame
CPU TIME:0 sec.
SCORE=551
*
BAD AVG GOOD
*
XP_019621834.1    :  56
XP_002611716.1    :  59
XP_019647399.1    :  63
XP_019647402.1    :  65
XP_019647400.1    :  63
XP_019625376.1    :  56
XP_002587789.1    :  56
XP_002611717.1    :  41
XP_002587789.1_   :  56
XP_019621834.1_   :  56
XP_019647400.1_   :  63
XP_019647399.1_   :  63
XP_019647402.1_   :  65
XP_019625376.1_   :  56
VEGF-C            :  48
VEGF-D            :  45
VEGF-A206         :  55
VEGF-A165         :  56
VEGF-A121         :  56
VEGF-B186         :  49
VEGF-B167         :  53
PlGF-1            :  48
VEGF-F            :  48
PDGF-A            :  45
PDGF-B            :  42
PDGF-C            :  42
PDGF-D            :  44
cons              :  55

XP_019621834.1    -----------------------MACFYGKL-N
XP_002611716.1    -----------------------MA--------
XP_019647399.1    MFSRHPSAKTAFSETILC------WAGRAKIPF
XP_019647402.1    ---------------------------------
XP_019647400.1    MALQ--SELRLILLLLTC------TAIQGEIPF
XP_019625376.1    ------------------MSMYISLGLSSLL--
XP_002587789.1    ------------------MSIFTSFVLLSSL--
XP_002611717.1    ---------------------------------
XP_002587789.1_   ------------------MSIFTSFVLLSSL--
XP_019621834.1_   -----------------------MACFYGKL-N
XP_019647400.1_   MALQ--SELRLILLLLTC------TAIQGEIPF
XP_019647399.1_   MFSRHPSAKTAFSETILC------WAGRAKIPF
XP_019647402.1_   ---------------------------------
XP_019625376.1_   ------------------MSMYISLGLSSLL--
VEGF-C            ---------MH------LLGFFSVAC---SL-L
VEGF-D            ---------MYR--EWVVVNVF-------MM-L
VEGF-A206         ---------MNFLLSWVHWSLALL--LY-----
VEGF-A165         ---------MNFLLSWVHWSLALL--LY-----
VEGF-A121         ---------MNFLLSWVHWSLALL--LY-----
VEGF-B186         M-----SPLLRRLL------LAAL--LQ-----
VEGF-B167         M-----SPLLRRLL------LAAL--LQ-----
PlGF-1            M------PVMRLFPCFLQLLAGLA--LP-----
VEGF-F            M-----AAYL--LA------VAILFCIQ-----
PDGF-A            M------RTLACLLLLGCGYLAHVLAEEAEIPR
PDGF-B            M-----NRCWALFLSL-CCYLRLVSAEGDPIPE
PDGF-C            ---------MS--L-FGLLLLTSALA-------
PDGF-D            ---------MHRLI-FVYTLICANFC-------

cons

XP_019621834.1    QV--QL--G----DSAMSVYSLFVLVSLLGKPF
XP_002611716.1    ----------------------------LG---
XP_019647399.1    QVLNKLLD--VK-NPADLFHLFNVSTDSIGPEM
XP_019647402.1    --------------------------------M
XP_019647400.1    QVLNKLLD--VK-NPADLFHLFNVSTDSIGPEM
XP_019625376.1    -V--VL--G---ATQRASSHEDRPVVPEI--PL
XP_002587789.1    -V--AL--G---ATQRAPSPEESLLTSEI--PV
XP_002611717.1    ----------------MSVYSLFVLVSLLGKPF
XP_002587789.1_   -V--AL--G---ATQRAPSPEESLLTSEI--PV
XP_019621834.1_   QV--QL--G----DSAMSVYSLFVLVSLLGKPF
XP_019647400.1_   QVLNKLLD--VK-NPADLFHLFNVSTDSIGPEM
XP_019647399.1_   QVLNKLLD--VK-NPADLFHLFNVSTDSIGPEM
XP_019647402.1_   --------------------------------M
XP_019625376.1_   -V--VL--G---ATQRASSHEDRPVVPEI--PL
VEGF-C            AA--ALLPGPREAPAAAAAFESGLDLS-DAEP-
VEGF-D            YV--QLVQG--------SSNEHG--------PV
VEGF-A206         -----L--HHAKWSQAA--------------PM
VEGF-A165         -----L--HHAKWSQAA--------------PM
VEGF-A121         -----L--HHAKWSQAA--------------PM
VEGF-B186         -----L--APAQAPVSQ--------------PD
VEGF-B167         -----L--APAQAPVSQ--------------PD
PlGF-1            -----A--VPPQWALSA----------------
VEGF-F            -----G--WPS-GTV------------------
PDGF-A            EVIERLARSQIH-SIRDLQRLLEI--DSVGSE-
PDGF-B            ELYEMLSDHSIR-SFDDLQRLLHG--DP-GEE-
PDGF-C            --------GQRQGTQAESNLSSK----------
PDGF-D            --------SCRDTSATPQSASIK----------

cons

XP_019621834.1    GYSHFDT--RSR-LDRYLAGVGSTEDLLRLYY-
XP_002611716.1    ---------------------------------
XP_019647399.1    --SGPSTDFIPDSVLRDDS--FPT--IAAKDK-
XP_019647402.1    --SGPSTDFIPDSVLRDDS--FPT--IAAKDK-
XP_019647400.1    --SGPSTDFIPDSVLRDDS--FPT--IAAKDK-
XP_019625376.1    ------------HIRQLLRNVTSYEEL------
XP_002587789.1    ------------EIQRLLRNVTSYEEL------
XP_002611717.1    GYSHFDT--RSR-LDRHLAGVGSTEDLIRLYY-
XP_002587789.1_   ------------EIQRLLRNVTSYEEL------
XP_019621834.1_   GYSHFDT--RSR-LDRYLAGVGSTEDLLRLYY-
XP_019647400.1_   --SGPSTDFIPDSVLRDDS--FPT--IAAKDK-
XP_019647399.1_   --SGPSTDFIPDSVLRDDS--FPT--IAAKDK-
XP_019647402.1_   --SGPSTDFIPDSVLRDDS--FPT--IAAKDK-
XP_019625376.1_   ------------HIRQLLRNVTSYEEL------
VEGF-C            -DAGEATAYASKDLEEQLRSVSSVDELMTVLY-
VEGF-D            KRSSQSTLERS---EQQIRAASSLEELLRITH-
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            --D--SLDT---SL-RAH-GVHATKHVPEKRPL
PDGF-B            --DGAELDL---NMTRSHSG-------GELESL
PDGF-C            -------FQFSSN-----------KE-------
PDGF-D            -------ALRNANLRR--------DE-------

cons

XP_019621834.1    PEDWRKIMCHMRG-GGERYQSDYQSDYSEDGSG
XP_002611716.1    ---WR--AC-QQG-GG-----------------
XP_019647399.1    P-----IRGRLGGLGGD------QGIVLLDDSA
XP_019647402.1    P-----IRGRLGGLGGD------QGIVLLDDSA
XP_019647400.1    P-----IRGRLGGLGGD------QGIVLLDDSA
XP_019625376.1    ---------------------------------
XP_002587789.1    ---------------------------------
XP_002611717.1    PQQWRKIMCHMRG-GGERYLSDYQSDYSEDGSG
XP_002587789.1_   ---------------------------------
XP_019621834.1_   PEDWRKIMCHMRG-GGERYQSDYQSDYSEDGSG
XP_019647400.1_   P-----IRGRLGGLGGD------QGIVLLDDSA
XP_019647399.1_   P-----IRGRLGGLGGD------QGIVLLDDSA
XP_019647402.1_   P-----IRGRLGGLGGD------QGIVLLDDSA
XP_019625376.1_   ---------------------------------
VEGF-C            PEYWKMYKCQLRK-GGWQHNREQANLNSR--TE
VEGF-D            SEDWKLWRCRLRL-------KSFTSMDSRSASH
VEGF-A206         ----------AEG-GGQNHHE------------
VEGF-A165         ----------AEG-GGQNHHE------------
VEGF-A121         ----------AEG-GGQNHHE------------
VEGF-B186         ----------APG----HQRK------------
VEGF-B167         ----------APG----HQRK------------
PlGF-1            ------------G-NGSSEVE------------
VEGF-F            ------------------QGQ------------
PDGF-A            P-----IRRK---------------------RS
PDGF-B            ------ARGR---------------------RS
PDGF-C            ----------------QNGVQ------------
PDGF-D            ----------------SNHLT------------

cons

XP_019621834.1    MGRS---AAAATMDL--MDIVN----KVDEEWE
XP_002611716.1    --------------------IN---TEVDEEWE
XP_019647399.1    LGRNPFLSEKVTVSRQGADVVTSLLSEID--F-
XP_019647402.1    LGRNPFLSEKVTVSRQGADVVTSLLSEID--F-
XP_019647400.1    LGRNPFLSEKVTVSRQGADVVTSLLSEID--F-
XP_019625376.1    ---------KTTFNL---DIFS----AADDRFS
XP_002587789.1    ---------KATFNL---DIFT----AEDDRFS
XP_002611717.1    MGRS---AAAATMDL--MDIVN----K-DSS-E
XP_002587789.1_   ---------KATFNL---DIFT----AEDDRFS
XP_019621834.1_   MGRS---AAAATMDL--MDIVN----KVDEEWE
XP_019647400.1_   LGRNPFLSEKVTVSRQGADVVTSLLSEID--F-
XP_019647399.1_   LGRNPFLSEKVTVSRQGADVVTSLLSEID--F-
XP_019647402.1_   LGRNPFLSEKVTVSRQGADVVTSLLSEID--F-
XP_019625376.1_   ---------KTTFNL---DIFS----AADDRFS
VEGF-C            ETIK---FAAAHYNT---EILK----SIDNEWR
VEGF-D            RSTR---FAATFYDI---ETLK----VIDEEWQ
VEGF-A206         -----------VVKF--MDV-----------YQ
VEGF-A165         -----------VVKF--MDV-----------YQ
VEGF-A121         -----------VVKF--MDV-----------YQ
VEGF-B186         -----------VVSW--IDV-----------YT
VEGF-B167         -----------VVSW--IDV-----------YT
PlGF-1            -----------VVPF--QEV-----------WG
VEGF-F            -----------VRPF--LEV-----------HE
PDGF-A            I-------------EEAVPAVCKTRTVI---Y-
PDGF-B            LG-------SLTIAEPAMIAECKTRTEV---F-
PDGF-C            ------------------D-PQ-----------
PDGF-D            ------------------DLYR-----------

cons

XP_019621834.1    KAF---CKPRETAVDAATELQAPTDVTYRPSCV
XP_002611716.1    KAF---CKPRETAVDAATELQAPTDVTYRPSCV
XP_019647399.1    ------CSPRGMEVKVPNE---RPSTIVVPSCV
XP_019647402.1    ------CSPRGMEVKVPNE---RPSTIVVPSCV
XP_019647400.1    ------CSPRGMEVKVPNE---RPSTIVVPSCV
XP_019625376.1    LTGPPPCIPREVPVPV--PVDAEPNVVLWPSCV
XP_002587789.1    LTGPPPCIPREMPVPV--PLDAEPNVVLWPSCV
XP_002611717.1    PYF-------E-VVGFWT--------THR-SLI
XP_002587789.1_   LTGPPPCIPREMPVPV--PLDAEPNVVLWPSCV
XP_019621834.1_   KAF---CKPRETAVDAATELQAPTDVTYRPSCV
XP_019647400.1_   ------CSPRGMEVKVPNE---RPSTIVVPSCV
XP_019647399.1_   ------CSPRGMEVKVPNE---RPSTIVVPSCV
XP_019647402.1_   ------CSPRGMEVKVPNE---RPSTIVVPSCV
XP_019625376.1_   LTGPPPCIPREVPVPV--PVDAEPNVVLWPSCV
VEGF-C            KTQ---CMPREVCIDVGKEFGVATNTFFKPPCV
VEGF-D            RTQ---CSPRETCVEVASELGKSTNTFFKPPCV
VEGF-A206         RSY---CHPIETLVDIFQEYPDEIEYIFKPSCV
VEGF-A165         RSY---CHPIETLVDIFQEYPDEIEYIFKPSCV
VEGF-A121         RSY---CHPIETLVDIFQEYPDEIEYIFKPSCV
VEGF-B186         RAT---CQPREVVVPLTVELMGTVAKQLVPSCV
VEGF-B167         RAT---CQPREVVVPLTVELMGTVAKQLVPSCV
PlGF-1            RSY---CRALERLVDVVSEYPSEVEHMFSPSCV
VEGF-F            RSA---CQARETLVPILQEYPDEISDIFRPSCV
PDGF-A            ------EIPRSQ---VDPT---SANFLIWPPCV
PDGF-B            ------EISRRL---IDRT---NANFLVWPPCV
PDGF-C            ---------HERIITV-----------------
PDGF-D            ---------RDETIQV-----------------

cons

XP_019621834.1    SVFRCGGCCN-DERYECIASEKNMVSKTIF-EV
XP_002611716.1    SVFRCGGCCN-DEMYECIASEKNMVSKTIF-EV
XP_019647399.1    NLQRCGGCCH-ADIFQCEPLEIKNTTITVM-KL
XP_019647402.1    NLQRCGGCCH-ADIFQCEPLEIKNTTITVM-KL
XP_019647400.1    NLQRCGGCCH-ADIFQCEPLEIKNTTITVM-KL
XP_019625376.1    SVARCGGCCN-SDLYECQATRS---SSQVS-SI
XP_002587789.1    SVARCGGCCN-SDLYECQASRS---SSQVF-SV
XP_002611717.1    DVWVCAGHREVSEQPSCEAFARQLWGLFSFDEV
XP_002587789.1_   SVARCGGCCN-SDLYECQASRS---SSQVF-SV
XP_019621834.1_   SVFRCGGCCN-DERYECIASEKNMVSKTIF-EV
XP_019647400.1_   NLQRCGGCCH-ADIFQCEPLEIKNTTITVM-KL
XP_019647399.1_   NLQRCGGCCH-ADIFQCEPLEIKNTTITVM-KL
XP_019647402.1_   NLQRCGGCCH-ADIFQCEPLEIKNTTITVM-KL
XP_019625376.1_   SVARCGGCCN-SDLYECQATRS---SSQVS-SI
VEGF-C            SVYRCGGCCN-SEGLQCMNTSTSYLSKTLF-EI
VEGF-D            NVFRCGGCCN-EESLICMNTSTSYISKQLF-EI
VEGF-A206         PLMRCGGCCN-DEGLECVPTEESNITMQIM-RI
VEGF-A165         PLMRCGGCCN-DEGLECVPTEESNITMQIM-RI
VEGF-A121         PLMRCGGCCN-DEGLECVPTEESNITMQIM-RI
VEGF-B186         TVQRCGGCCP-DDGLECVPTGQHQVRMQIL-MI
VEGF-B167         TVQRCGGCCP-DDGLECVPTGQHQVRMQIL-MI
PlGF-1            SLLRCTGCCG-DENLHCVPVETANVTMQLL-KI
VEGF-F            AVLRCSGCCT-DESLKCTPVGKHTVDLQIM-RV
PDGF-A            EVKRCTGCCN-TSSVKCQPSRVHHRSVKVA-KV
PDGF-B            EVQRCSGCCN-NRNVQCRPTQVQLRPVQVR-KI
PDGF-C            ---STNG------------------------SI
PDGF-D            ---KGNG------------------------YV

cons                    *                         :

XP_019621834.1    GL---RGP-YPVTRPF---------ENHTRCEC
XP_002611716.1    GL---RGP-NPVTKPF---------ENHTRCEC
XP_019647399.1    GL----AEGGDLVL---EAIEGIEMEEHASCQC
XP_019647402.1    GL----AEGGDLVL---EAIEGIEMEEHASCQC
XP_019647400.1    GL----AEGGDLVL---EAIEGIEMEEHASCQC
XP_019625376.1    -LKLFYAPGNPNSQPFNTAFDQVHVERHDECAC
XP_002587789.1    -LKLFYSPGNPSSQPFNNAFDQVQVERHDQCAC
XP_002611717.1    G-----G--------------------------
XP_002587789.1_   -LKLFYSPGNPSSQPFNNAFDQVQVERHDQCAC
XP_019621834.1_   GL---RGP-YPVTRPF---------ENHTRCEC
XP_019647400.1_   GL----AEGGDLVL---EAIEGIEMEEHASCQC
XP_019647399.1_   GL----AEGGDLVL---EAIEGIEMEEHASCQC
XP_019647402.1_   GL----AEGGDLVL---EAIEGIEMEEHASCQC
XP_019625376.1_   -LKLFYAPGNPNSQPFNTAFDQVHVERHDECAC
VEGF-C            TVPLSQGP-KPVTISF---------ANHTSCRC
VEGF-D            SVPLTSVP-ELVPVKV---------ANHTGCKC
VEGF-A206         ------KP-HQGQH-----IGEMSFLQHNKCEC
VEGF-A165         ------KP-HQGQH-----IGEMSFLQHNKCEC
VEGF-A121         ------KP-HQGQH-----IGEMSFLQHNKCEC
VEGF-B186         --------RYPSSQ-----LGEMSLEEHSQCEC
VEGF-B167         --------RYPSSQ-----LGEMSLEEHSQCEC
PlGF-1            ------RSGDRPSY-----V-ELTFSQHVRCEC
VEGF-F            ------NPRTQSSK-----MEVMKFTEHTACEC
PDGF-A            EY----VRKKPKLK---EV--QVRLEEHLECAC
PDGF-B            EI----VRKKPIFK---KA--TVTLEDHLACKC
PDGF-C            -----HSPRFPHTYPRNTVL-------------
PDGF-D            -----QSPRFPNSYPRNLLL-------------

cons

XP_019621834.1    RAK----LGARTSFLYQRMNY---KR-------
XP_002611716.1    RAK----MGASSSFLFQRGNY---KR-------
XP_019647399.1    -----------------------------G--C
XP_019647402.1    -----------------------------G--C
XP_019647400.1    -----------------------------G--C
XP_019625376.1    VCKNKRLCDLRTHF-FDDNTCECVCRVRGG--C
XP_002587789.1    VCKNKHLCDLRTHF-FDDNTCDCVCRHRGG--C
XP_002611717.1    MAQ----TGNG------RQN-----R-------
XP_002587789.1_   VCKNKHLCDLRTHF-FDDNTCDCVCRHRGG--C
XP_019621834.1_   RAK----LGARTSFLYQRMNY---KR-------
XP_019647400.1_   -----------------------------G--C
XP_019647399.1_   -----------------------------G--C
XP_019647402.1_   -----------------------------G--C
XP_019625376.1_   VCKNKRLCDLRTHF-FDDNTCECVCRVRGG--C
VEGF-C            MSK----LD-----VY-RQVHSIIRR-------
VEGF-D            LPT----AP--------RHPYSIIRR-------
VEGF-A206         RP-KKD---------------------------
VEGF-A165         RP-KKD---------------------------
VEGF-A121         RP-KKD---------------------------
VEGF-B186         RPKKKD---------------------------
VEGF-B167         RPKKKD---------------------------
PlGF-1            RP-LRE---------------------------
VEGF-F            RPRRKQ---------------------------
PDGF-A            -----------------------------ATTS
PDGF-B            -----------------------------ETVA
PDGF-C            -----------------------VWR-------
PDGF-D            -----------------------TWR-------

cons

XP_019621834.1    AVSPHI--NTRCYAPNKTCGPYE-KWDDRDCAC
XP_002611716.1    AVSPHV--NTRCYAPNKTCGPHQ-KWDDRDCAC
XP_019647399.1    KVKPH------------HCNPTIHKYEDCACSC
XP_019647402.1    KVKPH------------HCNPTIHKYEDCACSC
XP_019647400.1    KVKPH------------HCNPTIHKYEDCACSC
XP_019625376.1    SVSA-VSDNL-C---NRQC-SAGFRLDEDSCRC
XP_002587789.1    VLGA-VSDDS-C---SRQC-PSGWKLDEDACQC
XP_002611717.1    I---KV--KTRL---------HS-VWARR----
XP_002587789.1_   VLGA-VSDDS-C---SRQC-PSGWKLDEDACQC
XP_019621834.1_   AVSPHI--NTRCYAPNKTCGPYE-KWDDRDCAC
XP_019647400.1_   KVKPH------------HCNPTIHKYEDCACSC
XP_019647399.1_   KVKPH------------HCNPTIHKYEDCACSC
XP_019647402.1_   KVKPH------------HCNPTIHKYEDCACSC
XP_019625376.1_   SVSA-VSDNL-C---NRQC-SAGFRLDEDSCRC
VEGF-C            SLPATLPQ---CQAANKTC-PTNYMWNNHICRC
VEGF-D            SI--QIPEEDRCSHSKKLC-PIDMLWDSNKCKC
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            L------------------NPD-YREED-----
PDGF-B            AARPV------------TRSPG-GSQEQRA---
PDGF-C            -LVA-VEENVWI----------QLTFDER----
PDGF-D            -LHS--QENTRI----------QLVFDNQ----

cons

XP_019621834.1    VRAVTII-------------DDD--D--H--CG
XP_002611716.1    VSDLTVI-------------ADD--D--H--CG
XP_019647399.1    LSP---------RR--------D--------CE
XP_019647402.1    LSP---------RR--------D--------CE
XP_019647400.1    LSP---------RR--------D--------CE
XP_019625376.1    RVDGGALFGGLGRR-------------------
XP_002587789.1    RLDGRALFGSLGRRCVLGAVSDDSCS--RQ-C-
XP_002611717.1    ---------------------------------
XP_002587789.1_   RLDGRALFGSLGRRCVLGAVSDDSCS--RQ-C-
XP_019621834.1_   VRAVTII-------------DDD--D--H--CG
XP_019647400.1_   LSP---------RR--------D--------CE
XP_019647399.1_   LSP---------RR--------D--------CE
XP_019647402.1_   LSP---------RR--------D--------CE
XP_019625376.1_   RVDGGALFGGLGRR-------------------
VEGF-C            LAQEDFMFSSD--------AGDDSTDGFHDICG
VEGF-D            VLQEE---NPL--------AGTE--DHSH----
VEGF-A206         -----------------RA-RQEK---------
VEGF-A165         -----------------RA-RQE----------
VEGF-A121         -----------------RA-RQEK---------
VEGF-B186         -----------------SAVKPD----------
VEGF-B167         -----------------SAVKPDS---------
PlGF-1            -----------------KM-KPER---------
VEGF-F            -----------------G--EPDG---------
PDGF-A            ---------------------------------
PDGF-B            KTP------------------------------
PDGF-C            -------FG-------LEDPEDD----------
PDGF-D            -------FG-------LEEAEND----------

cons

XP_019621834.1    PLKEWREDECACVCK----RP--C-PQ-RFIE-
XP_002611716.1    PLKEWREDECACVCK----RP--C-PR-RFIE-
XP_019647399.1    EGKVWDEKECQCVCR------------------
XP_019647402.1    EGKVWDEKECQCVCR------------------
XP_019647400.1    EGKVWDEKECQCVCR------------------
XP_019625376.1    ----------------------------RR---
XP_002587789.1    P-SGWKLDEDACQCRLDG-R-ALFGSLGRRIQG
XP_002611717.1    PV-----------------RP--L-SR-ALL--
XP_002587789.1_   P-SGWKLDEDACQCRLDG-R-ALFGSLGRRIQG
XP_019621834.1_   PLKEWREDECACVCK----RP--C-PQ-RFIE-
XP_019647400.1_   EGKVWDEKECQCVCR------------------
XP_019647399.1_   EGKVWDEKECQCVCR------------------
XP_019647402.1_   EGKVWDEKECQCVCR------------------
XP_019625376.1_   ----------------------------RR---
VEGF-C            PNKELDEETCQCVCRA-GLRPASCGPH-KELDR
VEGF-D            ----LQE-------------PALCGPH------
VEGF-A206         -------------------KSVR--GKGK----
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         -------------------RAAT--P-------
VEGF-B167         P------------------RPLC--PRCT----
PlGF-1            -------------------R--R--PKGR----
VEGF-F            P--------------------------------
PDGF-A            ---------------------------------
PDGF-B            --------QTRVTIR------------------
PDGF-C            ------------ICKYDFVEVEEPSD-GTIL-G
PDGF-D            ------------ICRYDFVEVEDISETSTIIRG

cons

XP_019621834.1    ---------------------------------
XP_002611716.1    ---------------------------------
XP_019647399.1    --------------------------------S
XP_019647402.1    --------------------------------S
XP_019647400.1    --------------------------------S
XP_019625376.1    ---------------------------------
XP_002587789.1    SRAPGGQCEFEFHLVGNFVKTSNMSSSSSSPSS
XP_002611717.1    ---------------------------------
XP_002587789.1_   SRAPGGQCEFEFHLVGNFVKTSNMSSSSSSPSS
XP_019621834.1_   ---------------------------------
XP_019647400.1_   --------------------------------S
XP_019647399.1_   --------------------------------S
XP_019647402.1_   --------------------------------S
XP_019625376.1_   ---------------------------------
VEGF-C            NSC---QCVCKNKL---F------------PS-
VEGF-D            ---------------------------------
VEGF-A206         -----GQ--------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ------Q--------------------------
PlGF-1            -----G---------------------------
VEGF-F            ---------------------------------
PDGF-A            --------------------------------T
PDGF-B            --------------------------------T
PDGF-C            RWCGSGTVPGKQISKGNQIRIRFVS--------
PDGF-D            RWCGHKEVPPRIKSRTNQIKITFKS--------

cons

XP_019621834.1    ---------------------------------
XP_002611716.1    ---------------------------------
XP_019647399.1    GETNCRKRYYWSP--------------------
XP_019647402.1    GETNCRKRYYWSP--------------------
XP_019647400.1    GETNCRKRYYWSP--------------------
XP_019625376.1    ---------------------------------
XP_002587789.1    PEEQVDDEY-QPPGAAPFKLKSPPRG-KGIEP-
XP_002611717.1    ---------------------------------
XP_002587789.1_   PEEQVDDEY-QPPGAAPFKLKSPPRG-KGIEP-
XP_019621834.1_   ---------------------------------
XP_019647400.1_   GETNCRKRYYWSP--------------------
XP_019647399.1_   GETNCRKRYYWSP--------------------
XP_019647402.1_   GETNCRKRYYWSP--------------------
XP_019625376.1_   ---------------------------------
VEGF-C            ---QC--------GA------------------
VEGF-D            ---------------------------------
VEGF-A206         -------KR-K---------RKKSRY-KS----
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         -------HH-----------RPQPRSVPG----
VEGF-B167         -------HH-Q---------RPDPRT-------
PlGF-1            -------KR-R---------REKQR--------
VEGF-F            --------------------KEKPRR--G----
PDGF-A            G----RPR-------------------------
PDGF-B            V----RVR-------------------------
PDGF-C            -----DEYFPSEPG---FCIHYN--IV---MP-
PDGF-D            -----DDYFVAKPG---FKIYYS--LLEDFQPA

cons

XP_019621834.1    -------DL-----QTCEC--------------
XP_002611716.1    -------DP-----QTCEC--------------
XP_019647399.1    --------------DRCECL-------------
XP_019647402.1    --------------DRCECL-------------
XP_019647400.1    --------------DRCECL-------------
XP_019625376.1    ---------------------------------
XP_002587789.1    -KEDKDYEAKVGLGKTLQTISLLGYMKHYRSIP
XP_002611717.1    ---------------------------------
XP_002587789.1_   -KEDKDYEAKVGLGKTLQTISLLGYMKHYRSIP
XP_019621834.1_   -------DL-----QTCEC--------------
XP_019647400.1_   --------------DRCECL-------------
XP_019647399.1_   --------------DRCECL-------------
XP_019647402.1_   --------------DRCECL-------------
XP_019625376.1_   ---------------------------------
VEGF-C            ---NREFDE-----NTCQCVC------------
VEGF-D            ----MMFDE-----DRCECVC------------
VEGF-A206         ------WSVYVG--ARC-C-------LMPWSLP
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ------WD------SAPGA-------PSPADIT
VEGF-B167         --------------CRCRC-------RRRSFLR
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            --------------QFTEAV-------------
PDGF-D            AASETNWE------SVTSSISGVSY-------N

cons

XP_019621834.1    ----------R-----------CP---------
XP_002611716.1    ----------T-----------CP---------
XP_019647399.1    ----------------------C---------A
XP_019647402.1    ----------------------C---------A
XP_019647400.1    ----------------------C---------A
XP_019625376.1    ---------------------------------
XP_002587789.1    GPHLVIVPKSTLANWMNEFEHWCPSIRTVSLIG
XP_002611717.1    ---------------------------------
XP_002587789.1_   GPHLVIVPKSTLANWMNEFEHWCPSIRTVSLIG
XP_019621834.1_   ----------R-----------CP---------
XP_019647400.1_   ----------------------C---------A
XP_019647399.1_   ----------------------C---------A
XP_019647402.1_   ----------------------C---------A
XP_019625376.1_   ---------------------------------
VEGF-C            --------KRT-----------CP---------
VEGF-D            --------KTP-----------CP---------
VEGF-A206         GPH----P--------------C---------G
VEGF-A165         --N----P--------------C---------G
VEGF-A121         ---------------------------------
VEGF-B186         HPT----P--------------AP--------G
VEGF-B167         ----------------------CQ--------G
PlGF-1            -PT----D--------------C----------
VEGF-F            --------------------------------G
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            SPS-VLPPSALPLDLLNN------AITAFSTLE
PDGF-D            SPS-VTDPT-LIADALDK------KIAEFDTVE

cons

XP_019621834.1    ---------------P---------Y-------
XP_002611716.1    ---------------P---------Y-------
XP_019647399.1    DR-------------P-----CPT---------
XP_019647402.1    DR-------------P-----CPT---------
XP_019647400.1    DR-------------P-----CPT---------
XP_019625376.1    ---------------------------------
XP_002587789.1    DQEKRAAIIRDQIM-PGEWDVCITSYEMALREK
XP_002611717.1    ---------------------------------
XP_002587789.1_   DQEKRAAIIRDQIM-PGEWDVCITSYEMALREK
XP_019621834.1_   ---------------P---------Y-------
XP_019647400.1_   DR-------------P-----CPT---------
XP_019647399.1_   DR-------------P-----CPT---------
XP_019647402.1_   DR-------------P-----CPT---------
XP_019625376.1_   ---------------------------------
VEGF-C            ---------RNQPLNPGK---C--AC-------
VEGF-D            ---------KDLIQHPKN---C--SC-------
VEGF-A206         ---------------P-----C---SE---RRK
VEGF-A165         ---------------P-----C---SE---RRK
VEGF-A121         ---------------------------------
VEGF-B186         ---------------P---------------SA
VEGF-B167         ---------------R---------------GL
PlGF-1            ---------------------------------
VEGF-F            ---------------V---------------RA
PDGF-A            -E---------------------S---------
PDGF-B            -R-------------P------PK---------
PDGF-C            D------LIR--YLEPERW-------QLDLED-
PDGF-D            D------LLK--YFNPESW-------QEDLEN-

cons

XP_019621834.1    ---------Y------------------Q----
XP_002611716.1    ---------Y------------------R----
XP_019647399.1    -----------GRTL------------------
XP_019647402.1    -----------GRTL------------------
XP_019647400.1    -----------GRTL------------------
XP_019625376.1    ---------------------------------
XP_002587789.1    AVFKKFNWRYL----VIDEAHRIKNEKSKLSEI
XP_002611717.1    ---------------------------------
XP_002587789.1_   AVFKKFNWRYL----VIDEAHRIKNEKSKLSEI
XP_019621834.1_   ---------Y------------------Q----
XP_019647400.1_   -----------GRTL------------------
XP_019647399.1_   -----------GRTL------------------
XP_019647402.1_   -----------GRTL------------------
XP_019625376.1_   ---------------------------------
VEGF-C            ----------------------------ECTE-
VEGF-D            ---------F------------------ECKE-
VEGF-A206         HLF------------------------------
VEGF-A165         HLF------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         HA-------------------------------
VEGF-B167         EL-------------------------------
PlGF-1            HL-------------------------------
VEGF-F            KF-------------------------------
PDGF-A            -----------G---------------------
PDGF-B            -----------G---------------------
PDGF-C            -LYRP-TWQLLGKAFVFGRKSRVV-DLNLLTEE
PDGF-D            -MYLD-TPRYRGRSY-HDRKSK-V-DLDRLNDD

cons

XP_019621834.1    -------TRCQKKG----QKLH-----------
XP_002611716.1    -------NRCQRIG----HRLH-----------
XP_019647399.1    ---------------------------------
XP_019647402.1    ---------------------------------
XP_019647400.1    ---------------------------------
XP_019625376.1    ---------------------------------
XP_002587789.1    VRTFKTTNRLLLTGTPLQNNLHELWSLLNFLLP
XP_002611717.1    ---------------------------------
XP_002587789.1_   VRTFKTTNRLLLTGTPLQNNLHELWSLLNFLLP
XP_019621834.1_   -------TRCQKKG----QKLH-----------
XP_019647400.1_   ---------------------------------
XP_019647399.1_   ---------------------------------
XP_019647402.1_   ---------------------------------
XP_019625376.1_   ---------------------------------
VEGF-C            -----SPQKCLLKG----KKFH-----------
VEGF-D            -----SLETCCQKH----KLFH-----------
VEGF-A206         ----------------VQD-------------P
VEGF-A165         ----------------VQD-------------P
VEGF-A121         ---------------------------------
VEGF-B186         ------------------A-------------P
VEGF-B167         ------------------N-------------P
PlGF-1            ---------------------------------
VEGF-F            --------------------------------P
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            VRLYS----C----TP-----------RNF---
PDGF-D            AKRYS----C----TP-----------RNY---

cons

XP_019621834.1    --------------W-GTCKC------VP----
XP_002611716.1    --------------W-GTCKC------VP----
XP_019647399.1    ------------D--FNTCKC--KRNTSRRLQD
XP_019647402.1    ------------D--FNTCKC--KRNTSRRLQD
XP_019647400.1    ------------D--FNTCKC--KRNTSRRLQD
XP_019625376.1    ---------------------------------
XP_002587789.1    DVFNSSEDF---DAWFDTNACLDKDDMVARLHT
XP_002611717.1    ----------------------------P----
XP_002587789.1_   DVFNSSEDF---DAWFDTNACLDKDDMVARLHT
XP_019621834.1_   --------------W-GTCKC------VP----
XP_019647400.1_   ------------D--FNTCKC--KRNTSRRLQD
XP_019647399.1_   ------------D--FNTCKC--KRNTSRRLQD
XP_019647402.1_   ------------D--FNTCKC--KRNTSRRLQD
XP_019625376.1_   ---------------------------------
VEGF-C            --------------H-QTCSC----------YR
VEGF-D            --------------P-DTCSC---EDRCP-FHT
VEGF-A206         ----------------QTCKC------------
VEGF-A165         ----------------QTCKC------------
VEGF-A121         ---------------------------------
VEGF-B186         ----------------STTSA------------
VEGF-B167         ----------------DT---------------
PlGF-1            --------------------C------------
VEGF-F            ----------------FV---------------
PDGF-A            -----------------------KKRKRKR---
PDGF-B            -----------------------KHRKFKHTHD
PDGF-C            SV-SIREELKRTDTIFWP-GCL----LVKR---
PDGF-D            SV-NIREELKLANVVFFP-RCL----LVQR---

cons

XP_019621834.1    -----KD--C-HYVMACPAGT------------
XP_002611716.1    -----KI--C-HYVVACPMGT------------
XP_019647399.1    -S---RT-PCKRR---CPPG-----------AL
XP_019647402.1    -S---RT-PCKRR---CPPG-----------AL
XP_019647400.1    -S---RT-PCKRR---CPPG-----------AL
XP_019625376.1    -----RT--------------------------
XP_002587789.1    LSEIVRTFKTTNRLLL--TGTPLQNNLHELWSL
XP_002611717.1    -----ED--------------------------
XP_002587789.1_   LSEIVRTFKTTNRLLL--TGTPLQNNLHELWSL
XP_019621834.1_   -----KD--C-HYVMACPAGT------------
XP_019647400.1_   -S---RT-PCKRR---CPPG-----------AL
XP_019647399.1_   -S---RT-PCKRR---CPPG-----------AL
XP_019647402.1_   -S---RT-PCKRR---CPPG-----------AL
XP_019625376.1_   -----RT--------------------------
VEGF-C            -----RP--CTNRQKACEPGF------------
VEGF-D            -----RP--CASGKTACAKHC------------
VEGF-A206         --------SCKNTDSRCKAR---QLELNE----
VEGF-A165         --------SCKNTDSRCKAR---QLELNE----
VEGF-A121         ---------------------------------
VEGF-B186         --------L---TPGPAAA---------A----
VEGF-B167         ---------------------------------
PlGF-1            --------G----DA------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            -----KT--------------------------
PDGF-C            ---------CGGN---CACCL------------
PDGF-D            ---------CGGN---CGCGT------------

cons

XP_019621834.1    -------VYST--------DVCACV----MLA-
XP_002611716.1    -------VYSE--------DVCACV----MLA-
XP_019647399.1    LNR----------------RHCTC-SQGQ----
XP_019647402.1    LNR----------------RHCTC-SQGQ----
XP_019647400.1    LNR----------------RHCTC-SQGQ----
XP_019625376.1    ---------------------------------
XP_002587789.1    LNFLLPDVFNSSEDFDAWFDTNACLDKDDMVAR
XP_002611717.1    ---------------------------------
XP_002587789.1_   LNFLLPDVFNSSEDFDAWFDTNACLDKDDMVAR
XP_019621834.1_   -------VYST--------DVCACV----MLA-
XP_019647400.1_   LNR----------------RHCTC-SQGQ----
XP_019647399.1_   LNR----------------RHCTC-SQGQ----
XP_019647402.1_   LNR----------------RHCTC-SQGQ----
XP_019625376.1_   ---------------------------------
VEGF-C            -------SYSE--------EVCRCV--------
VEGF-D            -------RFPK--------EK-RAA----Q---
VEGF-A206         -------------------RTCRC-DK------
VEGF-A165         -------------------RTCRC-DK------
VEGF-A121         -----------------------C-DK------
VEGF-B186         -------------------ADAAA-SS------
VEGF-B167         ---------------------CRC-RK------
PlGF-1            --------------------------V------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            HN---------------C-NECQCV-PSKVTKK
PDGF-D            VN---------------W-RSCTCN-SGKTVKK

cons

XP_019621834.1    ---------GG----------------------
XP_002611716.1    ---------GG----------------------
XP_019647399.1    ---------G----------RGR---M------
XP_019647402.1    ---------G----------RGR---M------
XP_019647400.1    ---------G----------RGR---M------
XP_019625376.1    ---------------------------------
XP_002587789.1    LH-TYQ-PPGAAPFKLKSPPRG--K-------G
XP_002611717.1    ---------GL----------------------
XP_002587789.1_   LH-TYQ-PPGAAPFKLKSPPRG--K-------G
XP_019621834.1_   ---------GG----------------------
XP_019647400.1_   ---------G----------RGR---M------
XP_019647399.1_   ---------G----------RGR---M------
XP_019647402.1_   ---------G----------RGR---M------
XP_019625376.1_   ---------------------------------
VEGF-C            ----------PSYWK------------------
VEGF-D            ---------GPHSRK------------------
VEGF-A206         ------------------PRR------------
VEGF-A165         ------------------PRR------------
VEGF-A121         ------------------PRR------------
VEGF-B186         ------------------VAKG----------G
VEGF-B167         ------------------LRR------------
PlGF-1            ------------------PRR------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            --------------------------A------
PDGF-C            YHEVLQLRP-------KTGVRGLHK--SLTDVA
PDGF-D            YHEVLQFEPG----HIKR--RGRAKTMALVDIQ

cons

XP_019621834.1    -----------------
XP_002611716.1    -----------------
XP_019647399.1    LSPFLPFDY---GSGDN
XP_019647402.1    LSPFLPFDY---GSGDN
XP_019647400.1    LSPFLPFDY---GSGDN
XP_019625376.1    -EP--------------
XP_002587789.1    IEPKEDKDYEAKV----
XP_002611717.1    -----------------
XP_002587789.1_   IEPKEDKDYEAKV----
XP_019621834.1_   -----------------
XP_019647400.1_   LSPFLPFDY---GSGDN
XP_019647399.1_   LSPFLPFDY---GSGDN
XP_019647402.1_   LSPFLPFDY---GSGDN
XP_019625376.1_   -EP--------------
VEGF-C            -RPQM-------S----
VEGF-D            -NP--------------
VEGF-A206         -----------------
VEGF-A165         -----------------
VEGF-A121         -----------------
VEGF-B186         ----------A------
VEGF-B167         -----------------
PlGF-1            -----------------
VEGF-F            -----------------
PDGF-A            LKPT-------------
PDGF-B            LKETL-------GA---
PDGF-C            LEHHEECDCVCRGSTGG
PDGF-D            LDHHERCDCICSSRPPR

cons