Individual alignments and phylogenetic tree for taxon hemichordata

hemichordata

XP_002733316

PDGF-B

PREDICTED: vascular endothelial growth factor C [Saccoglossus kowalevskii]

None



           1                                               50
XP_002733316.2  ~~~~~~~~~~~~~~~~~~~~MWQLVFSAAAILALAHGEYDAIPASILYKM
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_002733316.2  RDVHSAEDFIRIFHRPKPPSGPGYHDEGPSGTDLPVVPVGPPGIPGLPSG
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_002733316.2  NPYVPDVSGGGSDE.VEHDDPYSIVADLPPCVPRLAMVPIPKDR..DPAV
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_002733316.2  FLWPPCVELHRCGGCCNNELFVCEATKTNSVDVKVYRTSFDQK.NPEALP
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_002733316.2  VEGIQTFRLTNETGCECSCKVKSDHCNLDIHRHENCQCVCKQPEK.....
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_002733316.2  ..GVTCMERKVWDESTCSCLCKASMSDRICYPRKKMWDDSTCQCECKR..
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGP.NKELDEETCQCVCRAGL
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_002733316.2  .TISCKEGYVWNIDKCRCERLKPFTVKHCPP...TDCPLGRLLMPPTCEC
VEGF-C          RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_002733316.2  IQPRDV~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_002733316.2  ~~~~~~~~~~~~~~~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

283464131

ADB22649

PDGF-B

vascular endothelial growth factor, partial [Saccoglossus kowalevskii]

None

blastp

alignment



           1                                               50
ADB22649.1      ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
ADB22649.1      ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
ADB22649.1      ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           151                                            200
ADB22649.1      ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~PIPKD
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           201                                            250
ADB22649.1      RDPAVFLWPPCVELHRCG.GCCNNELFVCEATKTNSVDVKVYRTSFDQKN
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
VEGFC_signature ~~~~~~~~~~CXXXXXCXXXXXXXXXXXXXXXXPXCVXX.XRCXGCCXXX

           251                                            300
ADB22649.1      PEALPVEGIQTFRLTNETGCECSCKVKSDHCNLDIHRHENCQCVCKQPEK
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
VEGFC_signature XXXCXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXCXC~~~~~~~

           301                                            350
ADB22649.1      GVTCMERKVWDESTCSCLCKASMSDRICYPRKKMWDDSTCQCECKRTISC
VEGF-C          PASCGPHKELDRNSCQCVCKNKLFPSQCGAN.REFDENTCQCVCKRTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
ADB22649.1      KEGYVWNIDKCRCERLKPFTVKHCPPTDCPLGRLLMPPTCECIQPRDV~~
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
ADB22649.1      ~~~~~~~~~~~~~~~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

585650688

XP_006814626

VEGF-B167

PREDICTED: uncharacterized protein LOC102807434, partial [Saccoglossus kowalevskii], PDGF signature programmatically detected

None

blastp

alignment



           1                                               50
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~MINREASKARCKPRDTVVDVYKELGLHKGI
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVAT.N
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXX.X

           151                                            200
XP_006814626.1  SLIFPECVLVQRCE.....NNGCCHDTQECKVDVNQTRNVSMLFITPTPA
VEGF-C          TFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPV
VEGFC_signature XXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_006814626.1  FRNISMDKSCSCQNKPGFCPESYPCPDGGLWDSVTCGCQCKKRCPFPFVL
VEGF-C          TISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMW
VEGFC_signature XXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_006814626.1  DRIK~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGL
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

585675253

XP_006818745

VEGF-D

PREDICTED: vascular endothelial growth factor C-like [Saccoglossus kowalevskii]

VEGF-C

blastp

alignment



           1                                               50
XP_006818745.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_006818745.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MAKLSASI
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_006818745.1  VILNLCVYLLSSPVSVIGFKNLFPHFYETPSQKILEIEEADTIQDVLAIL
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_006818745.1  FPSEDPSDVWRTLEVREGLSASPGGRFSPGDEEIIWKNRTTSEMQEQDIP
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_006818745.1  RINNQKAESDCKTPVDQIVDSY....EELHIVEGLNTHIWPDCFMVQRCS
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_006818745.1  DTSGCCPTGHICQLKAGSTTMVEKMFLVFTINNNGVSQTHIAMKNVTSHG
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_006818745.1  DCECIAAVESIEN.SACSKP....PRLCPDAKEWNSNTCSCECSKKCPPP
VEGF-C          PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_006818745.1  YLRDPNSCVCECLHSDRSCGQVKRGLTLLPPSGCECVASGECADPACKSG
VEGF-C          QPLNPGKCACECTESPQKCLLKGKKFHHQTCS.CYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_006818745.1  FFASSQCKCIVYNK~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

XP_006814626.1

XP_006814626

PDGF-D

PREDICTED: uncharacterized protein LOC102807434, partial [Saccoglossus kowalevskii]

None

blastp

alignment



           1                                               50
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~MINREASKARCKPRDTVVDVYKELGLHKGI
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVAT.N
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXX.X

           151                                            200
XP_006814626.1  SLIFPECVLVQRCE.....NNGCCHDTQECKVDVNQTRNVSMLFITPTPA
VEGF-C          TFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPV
VEGFC_signature XXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_006814626.1  FRNISMDKSCSCQNKPGFCPESYPCPDGGLWDSVTCGCQCKKRCPFPFVL
VEGF-C          TISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMW
VEGFC_signature XXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_006814626.1  DRIK~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGL
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_006814626.1  ~~~~~~~~~~~~~~~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

XP_006818745.1

XP_006818745

PDGF-D

PREDICTED: vascular endothelial growth factor C-like [Saccoglossus kowalevskii]

None

blastp

alignment



           1                                               50
XP_006818745.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
VEGF-C          MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           51                                             100
XP_006818745.1  ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MAKLSASI
VEGF-C          YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           101                                            150
XP_006818745.1  VILNLCVYLLSSPVSVIGFKNLFPHFYETPSQKILEIEEADTIQDVLAIL
VEGF-C          SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX

           151                                            200
XP_006818745.1  FPSEDPSDVWRTLEVREGLSASPGGRFSPGDEEIIWKNRTTSEMQEQDIP
VEGF-C          FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT
VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX

           201                                            250
XP_006818745.1  RINNQKAESDCKTPVDQIVDSY....EELHIVEGLNTHIWPDCFMVQRCS
VEGF-C          ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN
VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           251                                            300
XP_006818745.1  DTSGCCPTGHICQLKAGSTTMVEKMFLVFTINNNGVSQTHIAMKNVTSHG
VEGF-C          NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           301                                            350
XP_006818745.1  DCECIAAVESIEN.SACSKP....PRLCPDAKEWNSNTCSCECSKKCPPP
VEGF-C          PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRN
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

           351                                            400
XP_006818745.1  YLRDPNSCVCECLHSDRSCGQVKRGLTLLPPSGCECVASGECADPACKSG
VEGF-C          QPLNPGKCACECTESPQKCLLKGKKFHHQTCS.CYRRPCTNRQKACEPGF
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

                401              420
XP_006818745.1  FFASSQCKCIVYNK~~~~~~
VEGF-C          SYSEEVCRCVPSYWKRPQMS
VEGFC_signature ~~~~~~~~~~~~~~~~~~~~

T-COFFEE, Version_11.00.8cbe486 (2014-08-12 22:05:29 - Revision 8cbe486 - Build 477)
Cedric Notredame
CPU TIME:0 sec.
SCORE=821
*
BAD AVG GOOD
*
XP_002733316.2    :  79
ADB22649.1        :  80
XP_006814626.1    :  83
XP_006818745.1    :  83
XP_006814626.1_   :  83
XP_006818745.1_   :  83
VEGF-C            :  81
VEGF-D            :  82
VEGF-A206         :  85
VEGF-A165         :  87
VEGF-A121         :  90
VEGF-B186         :  82
VEGF-B167         :  86
PlGF-1            :  88
VEGF-F            :  87
PDGF-A            :  81
PDGF-B            :  81
PDGF-C            :  85
PDGF-D            :  82
cons              :  82

XP_002733316.2    ---------------------------------
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ---------------------------------
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ---------------------------------
VEGF-C            ---------------------------------
VEGF-D            ---------------------------------
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            --MSLFGLLLLTSALAGQRQGTQAESNLSSKFQ
PDGF-D            MHRLIFVYTLICANFCSCRDTSATPQSASIKAL

cons

XP_002733316.2    ---------------------------------
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ---------------------------------
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ---------------------------------
VEGF-C            ---------------------------------
VEGF-D            ---------------------------------
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            FSSN---KEQNGVQDP-QHERIITVSTNGSIHS
PDGF-D            RNANLRRDESNHLTDLYRRDETIQVKGNGYVQS

cons

XP_002733316.2    -------------MWQL----------------
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ---------------------------------
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ---------------------------------
VEGF-C            ---------------------------------
VEGF-D            ---------------------------------
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ----------MRTLACL----------------
PDGF-B            ----------MNRCWAL----------------
PDGF-C            PRFPHTYPRNTVLVWRLVAVEENVWIQLTFDER
PDGF-D            PRFPNSYPRNLLLTWRLHS-QENTRIQLVFDNQ

cons

XP_002733316.2    ---------------------------------
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ---------------------------------
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ---------------------------------
VEGF-C            ---------------------------------
VEGF-D            ---------------------------------
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            FGLEDPEDDICKYDFVEVEEPSDGTIL--GRWC
PDGF-D            FGLEEAENDICRYDFVEVEDISETSTIIRGRWC

cons

XP_002733316.2    -----------------------------V---
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    -----------------MAKLSASIVILNLC-V
XP_006814626.1_   ---------------------------------
XP_006818745.1_   -----------------MAKLSASIVILNLC-V
VEGF-C            --------------------MHLLGFFSVACSL
VEGF-D            --------------------MYREWVVVNV-FM
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            -----------------------------L---
PDGF-B            -----------------------------F---
PDGF-C            GSGTVPGKQISKGNQIRIRFVSDEYFPSEPG-F
PDGF-D            GHKEVPPRIKSRTNQIKITFKSDDYFVAKPG-F

cons

XP_002733316.2    --FSAAAIL------------------------
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    Y---LLSSP------------------V--SVI
XP_006814626.1_   ---------------------------------
XP_006818745.1_   Y---LLSSP------------------V--SVI
VEGF-C            LAAA-L-LPGPREAPA----AAAAFESGLD-LS
VEGF-D            MLYVQL-V---QGSS------------------
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            --LLGCGYL------------------------
PDGF-B            --LSLCCYL------------------------
PDGF-C            CIHYNIVMPQFTEAV------------------
PDGF-D            KIYYSL-LEDFQPAAASETNWESVTSSISGVSY

cons

XP_002733316.2    ---ALAHGEYDAIP-ASILYKMRDV--HSAEDF
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    GF-KNLFPHFYETP-SQKILEIEE--ADTIQDV
XP_006814626.1_   ---------------------------------
XP_006818745.1_   GF-KNLFPHFYETP-SQKILEIEE--ADTIQDV
VEGF-C            DAEPDAGEATAYAS-KDLEEQLRS--VSSVDEL
VEGF-D            NEHGPVKRSSQSTL-ERSEQQIRA--ASSLEEL
VEGF-A206         -----------------------------MNFL
VEGF-A165         -----------------------------MNFL
VEGF-A121         -----------------------------MNFL
VEGF-B186         -------------------------------MS
VEGF-B167         -------------------------------MS
PlGF-1            --------------------------MPVMRLF
VEGF-F            ---------------------------------
PDGF-A            ---AHVLAEEAEIP-REVIERLARSQIHSIRDL
PDGF-B            ---RLVSAEGDPIP-EELYEMLSDHSIRSFDDL
PDGF-C            ---SPSVLPPSALPLDLLNNAITA--FSTLEDL
PDGF-D            N--SPSVTDPTLIA-DALDKKIAE--FDTVEDL

cons

XP_002733316.2    IRIFHRPKPPSGPGYHDEGPSGTDLPVV-----
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    LAILF-PSEDPSDVWR---TLEVREGLS-ASPG
XP_006814626.1_   ---------------------------------
XP_006818745.1_   LAILF-PSEDPSDVWR---TLEVREGLS-ASPG
VEGF-C            MTVLY--PEY----WK---MYKCQLRKGGWQHN
VEGF-D            LRITH--SED----WK---LWRCRLRLKSFT--
VEGF-A206         LSWVH----------W---SLALLLYLH-----
VEGF-A165         LSWVH----------W---SLALLLYLH-----
VEGF-A121         LSWVH----------W---SLALLLYLH-----
VEGF-B186         PLLRR----------L---LLAALLQLA-----
VEGF-B167         PLLRR----------L---LLAALLQLA-----
PlGF-1            PCFLQ----------L---LAGLALPAV-----
VEGF-F            --MAA-----------------YLLAVA-ILFC
PDGF-A            QRLLE--IDSVGS------EDSLDTSLR-----
PDGF-B            QRLLH--GDP-GE------EDGAELDLN-----
PDGF-C            IRYLE--------------PERWQLDLE-----
PDGF-D            LKYFN--------------PESWQEDLE-----

cons

XP_002733316.2    --PVGPPGIPGLPSGNPYVPDVSGGG-SDEVEH
ADB22649.1        ---------------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    G-RFSPGDEEIIWKNR---TTSEMQE-QDIP--
XP_006814626.1_   ---------------------------------
XP_006818745.1_   G-RFSPGDEEIIWKNR---TTSEMQE-QDIP--
VEGF-C            REQANLNSRTEETIKF----AAAHYNTEILK--
VEGF-D            --SMDSRSASHRSTRF----AATFYDIETLK--
VEGF-A206         --HAKWSQAAPMAEGG------GQNH-HEVV--
VEGF-A165         --HAKWSQAAPMAEGG------GQNH-HEVV--
VEGF-A121         --HAKWSQAAPMAEGG------GQNH-HEVV--
VEGF-B186         --PAQAPVSQPDAPGH------Q----RKVV--
VEGF-B167         --PAQAPVSQPDAPGH------Q----RKVV--
PlGF-1            --PPQWA----LSAGN------GSSE-VEVV--
VEGF-F            --IQGWPSGTVQ---------------GQVR--
PDGF-A            --AHGVHATKHVPEKRP-LPIRRKRS-I-----
PDGF-B            --MTRSHSGGELESLA-----RGRRS-LGSLTI
PDGF-C            --DLYRPTWQLLGKAF--VFGRKSRV-VDLN--
PDGF-D            --NMYLDTPRYRGRSY---HDRKSK--VDLD--

cons

XP_002733316.2    DDPYSIVADLPPCV-PRLAMVPIPK---D--RD
ADB22649.1        ---------------------PIPK---D--RD
XP_006814626.1    --MINREASKARCK-PRDTVVDVYKELGLHKGI
XP_006818745.1    --RINNQKAESDCKTPVDQIVDSYEELHIVEGL
XP_006814626.1_   --MINREASKARCK-PRDTVVDVYKELGLHKGI
XP_006818745.1_   --RINNQKAESDCKTPVDQIVDSYEELHIVEGL
VEGF-C            --SIDNEWRKTQCM-PREVCIDVGKEFGV--AT
VEGF-D            --VIDEEWQRTQCS-PRETCVEVASELGK--ST
VEGF-A206         --KFMDVYQRSYCH-PIETLVDIFQEYPD--EI
VEGF-A165         --KFMDVYQRSYCH-PIETLVDIFQEYPD--EI
VEGF-A121         --KFMDVYQRSYCH-PIETLVDIFQEYPD--EI
VEGF-B186         --SWIDVYTRATCQ-PREVVVPLTVELMG--TV
VEGF-B167         --SWIDVYTRATCQ-PREVVVPLTVELMG--TV
PlGF-1            --PFQEVWGRSYCR-ALERLVDVVSEYPS--EV
VEGF-F            --PFLEVHERSACQ-ARETLVPILQEYPD--EI
PDGF-A            -E----EAVPAVCK-TRTVIYEIPRSQVD--PT
PDGF-B            AE----PAMIAECK-TRTEVFEISRRLID--RT
PDGF-C            --LLTEEVRLYSCT-PRNFSVSIREEL---KRT
PDGF-D            --RLNDDAKRYSCT-PRNYSVNIREEL---KLA

cons

XP_002733316.2    PAVFL-WPPCVELHRCG---GCCNNELFVCEAT
ADB22649.1        PAVFL-WPPCVELHRCG---GCCNNELFVCEAT
XP_006814626.1    SL--IF-PECVLVQRC-ENNGCCHDTQ-ECKVD
XP_006818745.1    NT--HIWPDCFMVQRCSDTSGCCPTGHICQLKA
XP_006814626.1_   SL--IF-PECVLVQRC-ENNGCCHDTQ-ECKVD
XP_006818745.1_   NT--HIWPDCFMVQRCSDTSGCCPTGHICQLKA
VEGF-C            NT--FFKPPCVSVYRCG---GCCNSEGLQCMNT
VEGF-D            NT--FFKPPCVNVFRCG---GCCNEESLICMNT
VEGF-A206         EY--IFKPSCVPLMRCG---GCCNDEGLECVPT
VEGF-A165         EY--IFKPSCVPLMRCG---GCCNDEGLECVPT
VEGF-A121         EY--IFKPSCVPLMRCG---GCCNDEGLECVPT
VEGF-B186         AK--QLVPSCVTVQRCG---GCCPDDGLECVPT
VEGF-B167         AK--QLVPSCVTVQRCG---GCCPDDGLECVPT
PlGF-1            EH--MFSPSCVSLLRCT---GCCGDENLHCVPV
VEGF-F            SD--IFRPSCVAVLRCS---GCCTDESLKCTPV
PDGF-A            SANFLIWPPCVEVKRCT---GCCNTSSVKCQPS
PDGF-B            NANFLVWPPCVEVQRCS---GCCNNRNVQCRPT
PDGF-C            DT--IFWPGCLLVKRCGGNC---ACCLHNCNEC
PDGF-D            NV--VFFPRCLLVQRCGGNC---GCGTVNWRSC

cons                     * *. : **

XP_002733316.2    KTNSVDVKVYRTSFDQKNP------EALPVEGI
ADB22649.1        KTNSVDVKVYRTSFDQKNP------EALPVEGI
XP_006814626.1    VNQTRNVSMLFITPTPAFR--------------
XP_006818745.1    GSTTMVEKMFLVFTINNNG--V-----SQTH-I
XP_006814626.1_   VNQTRNVSMLFITPTPAFR--------------
XP_006818745.1_   GSTTMVEKMFLVFTINNNG--V-----SQTH-I
VEGF-C            STSYLSKTLFEITVPLSQG-----PK------P
VEGF-D            STSYISKQLFEISVPLTSV-----PE------L
VEGF-A206         EESNITMQIMRIKPHQGQH-------------I
VEGF-A165         EESNITMQIMRIKPHQGQH-------------I
VEGF-A121         EESNITMQIMRIKPHQGQH-------------I
VEGF-B186         GQHQVRMQILMIR-YPSSQ-------------L
VEGF-B167         GQHQVRMQILMIR-YPSSQ-------------L
PlGF-1            ETANVTMQLLKIRSGDRPS-------------Y
VEGF-F            GKHTVDLQIMRVNPRTQSS------K------M
PDGF-A            RVHHRSVKVAKVEYVRKKP------KLKEV---
PDGF-B            QVQLRPVQVRKIEIVRKKP------IFKKA---
PDGF-C            QCVPSKVTKKYHEVLQLRP---KTGVRGLHKSL
PDGF-D            TCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMAL

cons

XP_002733316.2    QTFRLTNETGCECSCKVK-SDHCN--------L
ADB22649.1        QTFRLTNETGCECSCKVK-SDHCN--------L
XP_006814626.1    -NISMDKS--CSCQ-------------------
XP_006818745.1    AMKNVTSHGDCECIAAVES-IENS---------
XP_006814626.1_   -NISMDKS--CSCQ-------------------
XP_006818745.1_   AMKNVTSHGDCECIAAVES-IENS---------
VEGF-C            VTISFANHTSCRCMSKLDV-YRQV--------H
VEGF-D            VPVKVANHTGCKCLPTAP---R-H--------P
VEGF-A206         GEMSFLQHNKCECRPKKDR-ARQEKKSVRGKGK
VEGF-A165         GEMSFLQHNKCECRPKKDR-ARQE---------
VEGF-A121         GEMSFLQHNKCECRPKKDR-ARQE---------
VEGF-B186         GEMSLEEHSQCECRPKKKD-SAVK---------
VEGF-B167         GEMSLEEHSQCECRPKKKD-SAVK---------
PlGF-1            VELTFSQHVRCECRPLREK-MKPE---------
VEGF-F            EVMKFTEHTACECRPRRKQ-GEPD---------
PDGF-A            -QVRLEEHLECACATTSLNPDYRE--------E
PDGF-B            -TVTLEDHLACKCETVAA--A------------
PDGF-C            TDVALEHHEECDCVCRGST-GG-----------
PDGF-D            VDIQLDHHERCDCICSSRP-PR-----------

cons                  .     * *

XP_002733316.2    DIHRHENC-------------------------
ADB22649.1        DIHRHENC-------------------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ---------------------------------
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ---------------------------------
VEGF-C            SIIRRSLP-------------ATL----PQ---
VEGF-D            YSIIRRSI-------------Q-I----PE---
VEGF-A206         GQKRKRKKSRYKSWSVYVGARCCLMPWSLPGPH
VEGF-A165         --------------------------------N
VEGF-A121         ---------------------------------
VEGF-B186         ----------------------------PD---
VEGF-B167         ----------------------------PDSPR
PlGF-1            --RR----------------------------R
VEGF-F            ---------------------------------
PDGF-A            DTGRPRES-------------------------
PDGF-B            ---------------------------------
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    --QCVCKQPEKG-------VTCMERKVWDESTC
ADB22649.1        --QCVCKQPEKG-------VTCMERKVWDESTC
XP_006814626.1    ----------------------NKP-------G
XP_006818745.1    ----ACSKPPRL---------CPDAKEWNSNTC
XP_006814626.1_   ----------------------NKP-------G
XP_006818745.1_   ----ACSKPPRL---------CPDAKEWNSNTC
VEGF-C            ---C--QAANKT---------CPTNYMWNNHIC
VEGF-D            --EDRCSHSKKL---------CPIDMLWDSNKC
VEGF-A206         P-CGPCSERRK-------HLFVQDPQT-----C
VEGF-A165         P-CGPCSERRK-------HLFVQDPQT-----C
VEGF-A121         ---------------------------------
VEGF-B186         ----RAATPHHRPQPRSVPGWDSAPGA-----P
VEGF-B167         PLCPRCTQHHQ----------RPDPRT-----C
PlGF-1            P-KGRGKRRRE-------K---QRPTD-----C
VEGF-F            --GPKEKPRRG----------G-----------
PDGF-A            --GKKRKRKRLK-------PT------------
PDGF-B            -------RPVTR-------SPGGSQEQRAKTPQ
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    SCLC-KAS-------------------------
ADB22649.1        SCLC-KAS-------------------------
XP_006814626.1    FCPE-SYP------------------C------
XP_006818745.1    SCEC-SKK------------------C------
XP_006814626.1_   FCPE-SYP------------------C------
XP_006818745.1_   SCEC-SKK------------------C------
VEGF-C            RCL-AQEDFMFSSDAGDDSTDGFHDICGPNKEL
VEGF-D            KCV-LQEE---NPLAGTEDHSHLQE--------
VEGF-A206         KCS-CKNT-------------------------
VEGF-A165         KCS-CKNT-------------------------
VEGF-A121         ---------------------------------
VEGF-B186         SPADITH--------------------------
VEGF-B167         RCRCRRRS-------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            TRVT-IR--------------------------
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    ------------MSDRIC---------------
ADB22649.1        ------------MSDRIC---------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ---------------------------------
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ---------------------------------
VEGF-C            DEETCQCVCRAGLRPASCGPHKELDRNSCQCVC
VEGF-D            ---------------------------------
VEGF-A206         ------------DS--RC---------------
VEGF-A165         ------------DS--RC---------------
VEGF-A121         ---------------------------------
VEGF-B186         -----------PTP--AP-GPSAHAA-------
VEGF-B167         -----------F-L--RC---------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            ---------------------------------
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    ---------YPRKKMWDDST--------CQCEC
ADB22649.1        ---------YPRKKMWDDST--------CQCEC
XP_006814626.1    ---------PDGGL-WDSVT--------CGCQC
XP_006818745.1    ---------PPPYL-RDPNS--------CVCEC
XP_006814626.1_   ---------PDGGL-WDSVT--------CGCQC
XP_006818745.1_   ---------PPPYL-RDPNS--------CVCEC
VEGF-C            KNKLFPSQCGANRE-FDENT--------CQCVC
VEGF-D            -----PALCGPHMM-FDEDR--------CECVC
VEGF-A206         ---------KARQLELNERT--------CRCDK
VEGF-A165         ---------KARQLELNERT--------CRCDK
VEGF-A121         -----------------------------KCDK
VEGF-B186         -----P---STTSALTPGPAAAAADAAASSVAK
VEGF-B167         ---------QGRGLELNPDT--------CRCRK
PlGF-1            ------------------HL--------CGDAV
VEGF-F            ----------------------------VRAKF
PDGF-A            ---------------------------------
PDGF-B            ----------T----------------------
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    KRTISCKEGYVWNIDKCRCE-RLKPFTVKHCPP
ADB22649.1        KRTISCKEGYVWNIDKCRCE-RLKPFTVKHCPP
XP_006814626.1    K--KRCPFPFVLDRIK-----------------
XP_006818745.1    L--HS---DRSCGQVKRGL--------------
XP_006814626.1_   K--KRCPFPFVLDRIK-----------------
XP_006818745.1_   L--HS---DRSCGQVKRGL--------------
VEGF-C            K--RTCPRNQPLNPGKCAC-------ECTESPQ
VEGF-D            K--TPCPKDLIQHPKNCSCF------ECKESLE
VEGF-A206         P--RR----------------------------
VEGF-A165         P--RR----------------------------
VEGF-A121         P--RR----------------------------
VEGF-B186         G--GA----------------------------
VEGF-B167         L--RR----------------------------
PlGF-1            P--RR----------------------------
VEGF-F            P--FV----------------------------
PDGF-A            ---------------------------------
PDGF-B            --------VRVRRPPKGKHRKFKHTHDKT----
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    TDCPLGRLLMPPTCECI----------------
ADB22649.1        TDCPLGRLLMPPTCECI----------------
XP_006814626.1    ---------------------------------
XP_006818745.1    ------TLLPPSGCECVASGEC-----AD--PA
XP_006814626.1_   ---------------------------------
XP_006818745.1_   ------TLLPPSGCECVASGEC-----AD--PA
VEGF-C            KCLLKGKKFHHQTCSC-YRRPC-----TNRQKA
VEGF-D            TCCQKHKLFHPDTCSCEDRCPFHTRPCASGKTA
VEGF-A206         ---------------------------------
VEGF-A165         ---------------------------------
VEGF-A121         ---------------------------------
VEGF-B186         ---------------------------------
VEGF-B167         ---------------------------------
PlGF-1            ---------------------------------
VEGF-F            ---------------------------------
PDGF-A            ---------------------------------
PDGF-B            -------------ALKE----------------
PDGF-C            ---------------------------------
PDGF-D            ---------------------------------

cons

XP_002733316.2    ----------------QPRDV-----
ADB22649.1        ----------------QPRDV-----
XP_006814626.1    --------------------------
XP_006818745.1    CKSGFF-ASSQCKCI--VYNK-----
XP_006814626.1_   --------------------------
XP_006818745.1_   CKSGFF-ASSQCKCI--VYNK-----
VEGF-C            CEPGFSYSEEVCRCV-PSYWKRPQMS
VEGF-D            CAKHCRFPKEKRAAQGPHSRKNP---
VEGF-A206         --------------------------
VEGF-A165         --------------------------
VEGF-A121         --------------------------
VEGF-B186         --------------------------
VEGF-B167         --------------------------
PlGF-1            --------------------------
VEGF-F            --------------------------
PDGF-A            --------------------------
PDGF-B            ----------------TLGA------
PDGF-C            --------------------------
PDGF-D            --------------------------

cons

585651198	XP_002733316	PDGF-B	PREDICTED: vascular endothelial growth factor C [Saccoglossus kowalevskii]	None	blastp	alignment 1 50 XP_002733316.2 ~~~~~~~~~~~~~~~~~~~~MWQLVFSAAAILALAHGEYDAIPASILYKM VEGF-C MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 51 100 XP_002733316.2 RDVHSAEDFIRIFHRPKPPSGPGYHDEGPSGTDLPVVPVGPPGIPGLPSG VEGF-C YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 101 150 XP_002733316.2 NPYVPDVSGGGSDE.VEHDDPYSIVADLPPCVPRLAMVPIPKDR..DPAV VEGF-C SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX 151 200 XP_002733316.2 FLWPPCVELHRCGGCCNNELFVCEATKTNSVDVKVYRTSFDQK.NPEALP VEGF-C FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX 201 250 XP_002733316.2 VEGIQTFRLTNETGCECSCKVKSDHCNLDIHRHENCQCVCKQPEK..... VEGF-C ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 251 300 XP_002733316.2 ..GVTCMERKVWDESTCSCLCKASMSDRICYPRKKMWDDSTCQCECKR.. VEGF-C NHICRCLAQEDFMFSSDAGDDSTDGFHDICGP.NKELDEETCQCVCRAGL VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 301 350 XP_002733316.2 .TISCKEGYVWNIDKCRCERLKPFTVKHCPP...TDCPLGRLLMPPTCEC VEGF-C RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 351 400 XP_002733316.2 IQPRDV~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 401 420 XP_002733316.2 ~~~~~~~~~~~~~~~~~~~~ VEGF-C SYSEEVCRCVPSYWKRPQMS VEGFC_signature ~~~~~~~~~~~~~~~~~~~~
283464131	ADB22649	PDGF-B	vascular endothelial growth factor, partial [Saccoglossus kowalevskii]	None	blastp	alignment 1 50 ADB22649.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 51 100 ADB22649.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 101 150 ADB22649.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 151 200 ADB22649.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~PIPKD VEGF-C FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 201 250 ADB22649.1 RDPAVFLWPPCVELHRCG.GCCNNELFVCEATKTNSVDVKVYRTSFDQKN VEGF-C ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN VEGFC_signature ~~~~~~~~~~CXXXXXCXXXXXXXXXXXXXXXXPXCVXX.XRCXGCCXXX 251 300 ADB22649.1 PEALPVEGIQTFRLTNETGCECSCKVKSDHCNLDIHRHENCQCVCKQPEK VEGF-C NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR VEGFC_signature XXXCXXXXXXXXXXXXXXX.XXXXXXXXXXXXXXXXXXXXCXC~~~~~~~ 301 350 ADB22649.1 GVTCMERKVWDESTCSCLCKASMSDRICYPRKKMWDDSTCQCECKRTISC VEGF-C PASCGPHKELDRNSCQCVCKNKLFPSQCGAN.REFDENTCQCVCKRTCPR VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 351 400 ADB22649.1 KEGYVWNIDKCRCERLKPFTVKHCPPTDCPLGRLLMPPTCECIQPRDV~~ VEGF-C NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 401 420 ADB22649.1 ~~~~~~~~~~~~~~~~~~~~ VEGF-C SYSEEVCRCVPSYWKRPQMS VEGFC_signature ~~~~~~~~~~~~~~~~~~~~
585650688	XP_006814626	VEGF-B167	PREDICTED: uncharacterized protein LOC102807434, partial [Saccoglossus kowalevskii], PDGF signature programmatically detected	None	blastp	alignment 1 50 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 51 100 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 101 150 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~MINREASKARCKPRDTVVDVYKELGLHKGI VEGF-C SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVAT.N VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXX.X 151 200 XP_006814626.1 SLIFPECVLVQRCE.....NNGCCHDTQECKVDVNQTRNVSMLFITPTPA VEGF-C TFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPV VEGFC_signature XXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXX 201 250 XP_006814626.1 FRNISMDKSCSCQNKPGFCPESYPCPDGGLWDSVTCGCQCKKRCPFPFVL VEGF-C TISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMW VEGFC_signature XXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 251 300 XP_006814626.1 DRIK~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C NNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGL VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 301 350 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 351 400 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 401 420 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~ VEGF-C SYSEEVCRCVPSYWKRPQMS VEGFC_signature ~~~~~~~~~~~~~~~~~~~~
585675253	XP_006818745	VEGF-D	PREDICTED: vascular endothelial growth factor C-like [Saccoglossus kowalevskii]	VEGF-C	blastp	alignment 1 50 XP_006818745.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 51 100 XP_006818745.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MAKLSASI VEGF-C YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 101 150 XP_006818745.1 VILNLCVYLLSSPVSVIGFKNLFPHFYETPSQKILEIEEADTIQDVLAIL VEGF-C SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX 151 200 XP_006818745.1 FPSEDPSDVWRTLEVREGLSASPGGRFSPGDEEIIWKNRTTSEMQEQDIP VEGF-C FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX 201 250 XP_006818745.1 RINNQKAESDCKTPVDQIVDSY....EELHIVEGLNTHIWPDCFMVQRCS VEGF-C ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 251 300 XP_006818745.1 DTSGCCPTGHICQLKAGSTTMVEKMFLVFTINNNGVSQTHIAMKNVTSHG VEGF-C NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 301 350 XP_006818745.1 DCECIAAVESIEN.SACSKP....PRLCPDAKEWNSNTCSCECSKKCPPP VEGF-C PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 351 400 XP_006818745.1 YLRDPNSCVCECLHSDRSCGQVKRGLTLLPPSGCECVASGECADPACKSG VEGF-C QPLNPGKCACECTESPQKCLLKGKKFHHQTCS.CYRRPCTNRQKACEPGF VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 401 420 XP_006818745.1 FFASSQCKCIVYNK~~~~~~ VEGF-C SYSEEVCRCVPSYWKRPQMS VEGFC_signature ~~~~~~~~~~~~~~~~~~~~
XP_006814626.1	XP_006814626	PDGF-D	PREDICTED: uncharacterized protein LOC102807434, partial [Saccoglossus kowalevskii]	None	blastp	alignment 1 50 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 51 100 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 101 150 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~MINREASKARCKPRDTVVDVYKELGLHKGI VEGF-C SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVAT.N VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXX.X 151 200 XP_006814626.1 SLIFPECVLVQRCE.....NNGCCHDTQECKVDVNQTRNVSMLFITPTPA VEGF-C TFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPV VEGFC_signature XXXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXX 201 250 XP_006814626.1 FRNISMDKSCSCQNKPGFCPESYPCPDGGLWDSVTCGCQCKKRCPFPFVL VEGF-C TISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMW VEGFC_signature XXXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 251 300 XP_006814626.1 DRIK~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C NNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGL VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 301 350 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C RPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPR VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 351 400 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C NQPLNPGKCACECTESPQKCLLKGKKFHHQTCSCYRRPCTNRQKACEPGF VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 401 420 XP_006814626.1 ~~~~~~~~~~~~~~~~~~~~ VEGF-C SYSEEVCRCVPSYWKRPQMS VEGFC_signature ~~~~~~~~~~~~~~~~~~~~
XP_006818745.1	XP_006818745	PDGF-D	PREDICTED: vascular endothelial growth factor C-like [Saccoglossus kowalevskii]	None	blastp	alignment 1 50 XP_006818745.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ VEGF-C MHLLGFFSVACSLLAAALLPGPREAPAAAAAFESGLDLSDAEPDAGEATA VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 51 100 XP_006818745.1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~MAKLSASI VEGF-C YASKDLEEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 101 150 XP_006818745.1 VILNLCVYLLSSPVSVIGFKNLFPHFYETPSQKILEIEEADTIQDVLAIL VEGF-C SRTEETIKFAAAHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNT VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~CXXXXXCXXXXXXXXXXXXX 151 200 XP_006818745.1 FPSEDPSDVWRTLEVREGLSASPGGRFSPGDEEIIWKNRTTSEMQEQDIP VEGF-C FFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVT VEGFC_signature XXXPXCVXXXRCXGCCXXXXXXCXXXXXXXXXXXXXXXXXXXXXXXXXXX 201 250 XP_006818745.1 RINNQKAESDCKTPVDQIVDSY....EELHIVEGLNTHIWPDCFMVQRCS VEGF-C ISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQCQAANKTCPTNYMWN VEGFC_signature XXXXXXXXCXC~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 251 300 XP_006818745.1 DTSGCCPTGHICQLKAGSTTMVEKMFLVFTINNNGVSQTHIAMKNVTSHG VEGF-C NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQCVCRAGLR VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 301 350 XP_006818745.1 DCECIAAVESIEN.SACSKP....PRLCPDAKEWNSNTCSCECSKKCPPP VEGF-C PASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRN VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 351 400 XP_006818745.1 YLRDPNSCVCECLHSDRSCGQVKRGLTLLPPSGCECVASGECADPACKSG VEGF-C QPLNPGKCACECTESPQKCLLKGKKFHHQTCS.CYRRPCTNRQKACEPGF VEGFC_signature ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 401 420 XP_006818745.1 FFASSQCKCIVYNK~~~~~~ VEGF-C SYSEEVCRCVPSYWKRPQMS VEGFC_signature ~~~~~~~~~~~~~~~~~~~~