| 1508640881 | RNA09057 | PDGF-B | platelet-derived growth factor subunit A isoform X1, partial [Brachionus plicatilis] | PDGF-A | blastp | alignment |
| RNA09057.1 | RNA09057 | PDGF-C | platelet-derived growth factor subunit A isoform X1, partial [Brachionus plicatilis] | PDGF-A | blastp | alignment |
T-COFFEE, Version_11.00.8cbe486 (2014-08-12 22:05:29 - Revision 8cbe486 - Build 477)
Cedric Notredame
CPU TIME:0 sec.
SCORE=837
*
BAD AVG GOOD
*
RNA09057.1 : 77
RNA09057.1_1 : 76
VEGF-C : 88
VEGF-D : 82
VEGF-A206 : 85
VEGF-A165 : 87
VEGF-A121 : 87
VEGF-B186 : 85
VEGF-B167 : 86
PlGF-1 : 86
VEGF-F : 87
PDGF-A : 78
PDGF-B : 77
PDGF-C : 82
PDGF-D : 76
cons : 83
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C ------------------------------------
VEGF-D ------------------------------------
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C MS--LFGLLLLTSALAGQRQGTQAESNLSSKFQFSS
PDGF-D MHRLIFVYTLICANFCSCRDTSATPQSASIKALRNA
cons
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C ------------------------------------
VEGF-D ------------------------------------
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C N---KEQNGVQDP-QHERIITVSTNGSIHSPRFPHT
PDGF-D NLRRDESNHLTDLYRRDETIQVKGNGYVQSPRFPNS
cons
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C ------------------------------------
VEGF-D ------------------------------------
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C YPRNTVLVWRLVAVEENVWIQLTFDERFGLEDPEDD
PDGF-D YPRNLLLTWRLHS-QENTRIQLVFDNQFGLEEAEND
cons
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C ------------------------------------
VEGF-D ------------------------------------
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C ICKYDFVEVEEPSDGTIL--GRWCGSGTVPGKQISK
PDGF-D ICRYDFVEVEDISETSTIIRGRWCGHKEVPPRIKSR
cons
RNA09057.1 -------------------------MLKALIFFF--
RNA09057.1_1 -------------------------MLKALIFFF--
VEGF-C --------MHLLGFFSVACSLLAAALLPGPREAP--
VEGF-D --------MYREWVVVNVFMMLYVQLVQGS------
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A --------------------------MRTLACLL--
PDGF-B --------------------------MNRCWALF--
PDGF-C GNQIRIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVS
PDGF-D TNQIKITFKSDDYFVAKPGFKIYYSLLEDFQPAAAS
cons
RNA09057.1 ---------------IFYDTITAQRKI--DSLSTKS
RNA09057.1_1 ---------------IFYDTITAQRKI--DSLSTKS
VEGF-C -AAAAAFESGLDLSDAEPDAGEATAYAS-KDLEEQL
VEGF-D -------------SNEHGPVKRSSQSTL-ERSEQQI
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ----------LLGCGYLAHVLAEEAEIP-REVIERL
PDGF-B ----------LSLCCYLRLVSAEGDPIP-EELYEML
PDGF-C P------------------SVLPPSALPLDLLNNAI
PDGF-D ETNWESVTSSISGVSYNSPSVTDPTLIA-DALDKKI
cons
RNA09057.1 K---EDLMKDLFKADGLAD-LAKMGVRFMHRPMG--
RNA09057.1_1 K---EDLMKDLFKADGLAD-LAKMGVRFMHRPMG--
VEGF-C RS--VSSVDELMTVLYPEYW-KMYKCQLRKGGWQHN
VEGF-D RA--ASSLEELLRITHSEDW-KLWRCRLRL----KS
VEGF-A206 ----MNFLLSWVHWSLALLL-YLHHAKWSQAAPM--
VEGF-A165 ----MNFLLSWVHWSLALLL-YLHHAKWSQAAPM--
VEGF-A121 ----MNFLLSWVHWSLALLL-YLHHAKWSQAAPM--
VEGF-B186 ------MSPLLRRLLLAALL-QLAPAQAPVSQPD--
VEGF-B167 ------MSPLLRRLLLAALL-QLAPAQAPVSQPD--
PlGF-1 -MPVMRLFPCFLQLLAGLAL-PAVPPQWA----L--
VEGF-F ----------MAAYLLAVAI-LFCIQGWPSGT----
PDGF-A ARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHG--
PDGF-B SDHSIRSFDDLQRLLHGDP-GEEDGAELDLNMTR--
PDGF-C TA--FSTLEDLIRYLEPERW-QLDLEDLYRPTWQ--
PDGF-D AE--FDTVEDLLKYFNPESW-QEDLENMYLDTPR--
cons
RNA09057.1 --LAGR------------------------------
RNA09057.1_1 --LAGR------------------------------
VEGF-C REQANLNS---RTEETI---KFAAAHYNTEILKSID
VEGF-D FTSMDSRS---ASHRST---RFAATFYDIETLKVID
VEGF-A206 --AEGGGQ---NHHEVV---KFM-------------
VEGF-A165 --AEGGGQ---NHHEVV---KFM-------------
VEGF-A121 --AEGGGQ---NHHEVV---KFM-------------
VEGF-B186 --APGHQ------RKVV---SWI-------------
VEGF-B167 --APGHQ------RKVV---SWI-------------
PlGF-1 --SAGNGS---SEVEVV---PFQ-------------
VEGF-F --VQ---------GQVR---PFL-------------
PDGF-A --VHATKH-------VP---EKR-------------
PDGF-B --SHSGGE-------LE---SLA-------------
PDGF-C --LLGKAFVFGRKSRVVDLNLLT-------------
PDGF-D --YRGRSY--HDRKSKVDLDRLN-------------
cons
RNA09057.1 ----TSSQSL---AEAKEATPGKCDPKPVCITNPLS
RNA09057.1_1 ----TSSQSL---AEAKEATPGKCDPKPVCITNPLS
VEGF-C NE-W---------------RKTQCMPREVCI--DVG
VEGF-D EE-W---------------QRTQCSPRETCV--EVA
VEGF-A206 DV-Y---------------QRSYCHPIETLV--DIF
VEGF-A165 DV-Y---------------QRSYCHPIETLV--DIF
VEGF-A121 DV-Y---------------QRSYCHPIETLV--DIF
VEGF-B186 DV-Y---------------TRATCQPREVVV--PLT
VEGF-B167 DV-Y---------------TRATCQPREVVV--PLT
PlGF-1 EV-W---------------GRSYCRALERLV--DVV
VEGF-F EV-H---------------ERSACQARETLV--PIL
PDGF-A PLPIRRKRSI------EEAVPAVCKTRTVIY--EIP
PDGF-B ----RGRRSLGSLTIAEPAMIAECKTRTEVF--EIS
PDGF-C EE-V---------------RLYSCTPRNFSV--SIR
PDGF-D DD-A---------------KRYSCTPRNYSV--NIR
cons * . :
RNA09057.1 SDLK---SNDQIAYPPCINIHRCDGCCPSNE-ECVA
RNA09057.1_1 SDLK---SNDQIAYPPCINIHRCDGCCPSNE-ECVA
VEGF-C KEFGV--ATNTFFKPPCVSVYRCGGCCNSEGLQCMN
VEGF-D SELGK--STNTFFKPPCVNVFRCGGCCNEESLICMN
VEGF-A206 QEYPD--EIEYIFKPSCVPLMRCGGCCNDEGLECVP
VEGF-A165 QEYPD--EIEYIFKPSCVPLMRCGGCCNDEGLECVP
VEGF-A121 QEYPD--EIEYIFKPSCVPLMRCGGCCNDEGLECVP
VEGF-B186 VELMG--TVAKQLVPSCVTVQRCGGCCPDDGLECVP
VEGF-B167 VELMG--TVAKQLVPSCVTVQRCGGCCPDDGLECVP
PlGF-1 SEYPS--EVEHMFSPSCVSLLRCTGCCGDENLHCVP
VEGF-F QEYPD--EISDIFRPSCVAVLRCSGCCTDESLKCTP
PDGF-A RSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQP
PDGF-B RRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRP
PDGF-C EEL-K--RTDTIFWPGCLLVKRCGGNCACCLHNCNE
PDGF-D EEL-K--LANVVFFPRCLLVQRCGGNCGCGTVNWRS
cons * *: : ** * *
RNA09057.1 IKTEELKLK--NVAVLALQN----G---QVAGYVGD
RNA09057.1_1 IKTEELKLK--NVAVLALQN----G---QVAGYVGD
VEGF-C TSTSYLSK-----TLFEITVP---L---SQGPKPVT
VEGF-D TSTSYISK-----QLFEISVP---L---TSVPELVP
VEGF-A206 TEESNITM-----QIMRIKP--------HQGQHIGE
VEGF-A165 TEESNITM-----QIMRIKP--------HQGQHIGE
VEGF-A121 TEESNITM-----QIMRIKP--------HQGQHIGE
VEGF-B186 TGQHQVRM-----QILMIR---------YPSSQLGE
VEGF-B167 TGQHQVRM-----QILMIR---------YPSSQLGE
PlGF-1 VETANVTM-----QLLKIRS--------GDRPSYVE
VEGF-F VGKHTVDL-----QIMRVNP----R---TQSSKMEV
PDGF-A SRVHHRSVKVAKVEYVRKKP----------KLKEVQ
PDGF-B TQVQLRPVQVRKIEIVRKKP----------IFKKAT
PDGF-C CQCVPSKVTKKYHEVLQLRP---KTGVRGLHKSLTD
PDGF-D CTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVD
cons .
RNA09057.1 VITVNNHTECECQCKWK-N-----------------
RNA09057.1_1 VITVNNHTECECQCKWK-N-----------------
VEGF-C -ISFANHTSCRCMSKLD-------------------
VEGF-D -VKVANHTGCKCLP--T-------------------
VEGF-A206 -MSFLQHNKCECRPKKDR-ARQEKKSVRGKGKGQKR
VEGF-A165 -MSFLQHNKCECRPKKDR-ARQE-------------
VEGF-A121 -MSFLQHNKCECRPKKDR-ARQE-------------
VEGF-B186 -MSLEEHSQCECRPKKKD-SAVK-------------
VEGF-B167 -MSLEEHSQCECRPKKKD-SAVK-------------
PlGF-1 -LTFSQHVRCECRPLREK-MKPE-----------RR
VEGF-F -MKFTEHTACECRPRRKQ-GEPD-------------
PDGF-A -VRLEEHLECACATTSL-NPDYR-------------
PDGF-B -VTLEDHLACKCETVAAARPVTR-------------
PDGF-C -VALEHHEECDCVCRGST-GG---------------
PDGF-D -IQLDHHERCDCICSSRP-PR---------------
cons : . .* * *
RNA09057.1 -------------------------------DNDCK
RNA09057.1_1 -------------------------------DNDCK
VEGF-C -----VYR-----------------------QVHSI
VEGF-D -----APR-----------------------HPYSI
VEGF-A206 KRKKSRYKSWSVYVGARCCLMPWSLPGPHP-CGPCS
VEGF-A165 ----------------------------NP-CGPCS
VEGF-A121 -K----------------------------------
VEGF-B186 ------------------------PDRAATPHHRPQ
VEGF-B167 ------------------------PDSPRPLCPRCT
PlGF-1 ----------------------------RP-KGRGK
VEGF-F -------------------------------GPKEK
PDGF-A -------------------------------EEDTG
PDGF-B -------------------------------SPGGS
PDGF-C ------------------------------------
PDGF-D ------------------------------------
cons
RNA09057.1 EVNQF-YVKHPYA--CECVCSD---HLFCGPLHHFD
RNA09057.1_1 EVNQF-YVKHPYA--CECVCSD---HLFCGPLHHFD
VEGF-C IRRSL-PATLPQ---CQAA------NKTCPTNYMWN
VEGF-D IRRSI---QIPEEDRCSHS------KKLCPIDMLWD
VEGF-A206 ERRKHLFVQDPQT--CKCSCKNT-DSRCKARQLELN
VEGF-A165 ERRKHLFVQDPQT--CKCSCKNT-DSRCKARQLELN
VEGF-A121 ------------------------------------
VEGF-B186 PRSVPGWDSAPG---APSPADITHPTPAPGPSAHAA
VEGF-B167 QHHQR---PDPRT--CRCRCRRRSFLRCQGRGLELN
PlGF-1 RRREK---QRPTD--C--------------------
VEGF-F PRRGG----------------VRAKFPFV-------
PDGF-A RPRES---GKKRK--RKRLKPT--------------
PDGF-B QEQRA---KTPQT--RVTIRTVRVRRPPKGKHRKFK
PDGF-C ------------------------------------
PDGF-D ------------------------------------
cons
RNA09057.1 RDSCSCKCHSK-------------------------
RNA09057.1_1 RDSCSCKCHSK-------------------------
VEGF-C NHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKEL
VEGF-D SNKCKCVLQEENPLA---GTEDHSHLQE--------
VEGF-A206 ERTCRCDKPRR-------------------------
VEGF-A165 ERTCRCDKPRR-------------------------
VEGF-A121 -----CDKPRR-------------------------
VEGF-B186 PSTTSALTPGP---AAAAADAAASSVAKGGA-----
VEGF-B167 PDTCRCRKLRR-------------------------
PlGF-1 -HLCGDAVPRR-------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B HTHDKTALKET-------------------------
PDGF-C ------------------------------------
PDGF-D ------------------------------------
cons
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C DEETCQCVCRAGLRPASCGPHKELDRNSCQCVCKNK
VEGF-D --------------PALCGPHMM-------------
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C ------------------------------------
PDGF-D ------------------------------------
cons
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C LFPSQCGANREFDENTCQCVCKRTCPRNQPLNPGKC
VEGF-D -----------FDEDRCECVCKTPCPKDLIQHPKNC
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C ------------------------------------
PDGF-D ------------------------------------
cons
RNA09057.1 ------------------------------------
RNA09057.1_1 ------------------------------------
VEGF-C AC-ECTESPQKCLLKGKKFHHQTCSC------YRRP
VEGF-D SCFECKESLETCCQKHKLFHPDTCSCEDRCPFHTRP
VEGF-A206 ------------------------------------
VEGF-A165 ------------------------------------
VEGF-A121 ------------------------------------
VEGF-B186 ------------------------------------
VEGF-B167 ------------------------------------
PlGF-1 ------------------------------------
VEGF-F ------------------------------------
PDGF-A ------------------------------------
PDGF-B ------------------------------------
PDGF-C ------------------------------------
PDGF-D ------------------------------------
cons
RNA09057.1 -----------FNLSEQSCKARGFSWNSNLC--
RNA09057.1_1 -----------FNLSEQSCKARGFSWNSNLC--
VEGF-C CTNRQKACEPGFSYSEEVCRCV-PSYWKRPQMS
VEGF-D CASGKTACAKHCRFPKEKRAAQGPHSRKNP---
VEGF-A206 ---------------------------------
VEGF-A165 ---------------------------------
VEGF-A121 ---------------------------------
VEGF-B186 ---------------------------------
VEGF-B167 ---------------------------------
PlGF-1 ---------------------------------
VEGF-F ---------------------------------
PDGF-A ---------------------------------
PDGF-B ---------------LGA---------------
PDGF-C ---------------------------------
PDGF-D ---------------------------------
cons